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Open reading frame 2 (6255-6887)


 FASTA searches a protein or DNA sequence data bank
 version 3.2t01  December 31, 1998
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

/tmp/fastainput376423: 211 aa
 >6255                6255..6887
 vs  SWISS PROT library
searching /disk2/data/fasta/swissprot36.fasta 0 library

       opt      E()
< 20   176     0:==
  22     0     0:           one = represents 114 library sequences
  24     0     0:
  26     3     2:*
  28    14    17:*
  30    91   101:*
  32   437   391:===*
  34  1247  1062:=========*=
  36  2457  2180:===================*==
  38  3979  3604:===============================*===
  40  5515  5027:============================================*====
  42  6471  6144:=====================================================*===
  44  6808  6778:===========================================================*
  46  6323  6903:========================================================   *
  48  6314  6609:======================================================== *
  50  5508  6031:=================================================   *
  52  4965  5302:============================================  *
  54  4351  4529:=======================================*
  56  3828  3783:=================================*
  58  3060  3106:===========================*
  60  2529  2516:======================*
  62  2193  2017:=================*==
  64  1730  1604:==============*=
  66  1358  1268:===========*
  68  1012   997:========*
  70   731   782:======*
  72   611   611:=====*
  74   469   476:====*
  76   339   371:===*
  78   267   288:==*
  80   218   224:=*
  82   146   171:=*
  84   106   136:=*
  86    76   105:*
  88    86    81:*          inset = represents 8 library sequences
  90    44    63:*
  92    49    49:*         :======*
  94    26    38:*         :====*
  96    14    29:*         :== *
  98    27    23:*         :==*=
 100    11    17:*         :==*
 102     7    13:*         :=*
 104     6    10:*         :=*
 106     8     8:*         :*
 108     6     6:*         :*
 110     4     5:*         :*
 112     1     4:*         :*
 114     2     3:*         :*
 116     3     2:*         :*
 118     5     2:*         :*
>120   388     1:*===      :*=======================================
26840295 residues in 74019 sequences
 statistics extrapolated from 50000 to 73492 sequences
  Expectation_n fit: rho(ln(x))= 5.8877+/-0.000515; mu= 1.3367+/- 0.029;
 mean_var=74.4164+/-14.677, 0's: 142 Z-trim: 230  B-trim: 0 in 0/64
 Kolmogorov-Smirnov  statistic: 0.0232 (N=29) at  44

FASTA (3.2 December, 1998) function (optimized, BL50 matrix) ktup: 2
 join: 36, opt: 24, gap-pen: -12/ -2, width:  16 reg.-scaled
 Scan time: 28.470
The best scores are:                             initn init1 opt z-sc E(73492)
sp|P21447|MDR3_MOUSE MULTIDRUG RESISTANC  (1276)  635  347  348 403.0 8.9e-16
sp|P06795|MDR1_MOUSE MULTIDRUG RESISTANC  (1276)  635  347  348 403.0 8.9e-16
sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE   (1278)  606  337  345 399.6 1.4e-15
sp|P21440|MDR2_MOUSE MULTIDRUG RESISTANC  (1276)  607  337  343 397.3 1.9e-15
sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANC  (1276)  605  341  342 396.1 2.2e-15
sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANC  (1276)  605  341  342 396.1 2.2e-15
sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE   (1277)  629  341  342 396.1 2.2e-15
sp|P21439|MDR3_HUMAN MULTIDRUG RESISTANC  (1279)  577  331  341 394.9 2.5e-15
sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANC  (1281)  602  331  340 393.7 2.9e-15
sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANC  (1280)  596  332  337 390.3 4.6e-15
sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANC  (1321)  503  323  332 384.3 9.9e-15
sp|Q00748|MDR5_DROME MULTIDRUG RESISTANC  (1302)  485  287  302 349.6 8.5e-13
sp|Q00449|MDR4_DROME MULTIDRUG RESISTANC  (1302)  493  264  278 321.8 3e-11
sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESIST  (1362)  433  269  273 315.7 6.6e-11
sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANC  (1254)  467  269  270 312.7 9.6e-11
sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANC  (1280)  413  247  265 306.8 2e-10
sp|P22638|HEPA_ANASP HETEROCYST DIFFEREN  ( 532)  256  231  255 301.2 4.2e-10
sp|P55122|HLYB_PASSP LEUKOTOXIN SECRETIO  ( 708)  340  211  253 296.9 7.3e-10
sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT   ( 587)  320  210  250 294.7 9.6e-10
sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT   ( 582)  320  208  249 293.6 1.1e-09
sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSP  ( 586)  235  235  249 293.6 1.1e-09
sp|P16532|HLYB_PASHA LEUKOTOXIN SECRETIO  ( 708)  335  211  250 293.5 1.1e-09
sp|P23702|HLYB_ACTAC LEUKOTOXIN SECRETIO  ( 707)  333  208  249 292.3 1.3e-09
sp|P10089|HLY2_ECOLI HEMOLYSIN SECRETION  ( 707)  348  226  247 290.0 1.8e-09
sp|P08716|HLYB_ECOLI HEMOLYSIN SECRETION  ( 707)  348  226  247 290.0 1.8e-09
sp|Q04473|RT3B_ACTPL RTX-III TOXIN DETER  ( 711)  326  204  245 287.6 2.4e-09
sp|Q57180|YA51_HAEIN HYPOTHETICAL ABC TR  ( 614)  353  223  244 287.5 2.4e-09
sp|P11599|HLYB_PROVU HEMOLYSIN SECRETION  ( 707)  344  226  244 286.5 2.8e-09
sp|P26760|RT1B_ACTPL RTX-I TOXIN DETERMI  ( 707)  328  211  244 286.5 2.8e-09
sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERAN  ( 830)  382  221  244 285.4 3.2e-09
sp|P18770|CYAB_BORPE CYCLOLYSIN SECRETIO  ( 712)  312  176  240 281.8 5e-09
sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TR  ( 575)  379  208  237 279.8 6.5e-09
sp|P33311|MDL2_YEAST ATP-DEPENDENT PERME  ( 820)  324  198  239 279.7 6.6e-09
sp|P22520|CVAB_ECOLI COLICIN V SECRETION  ( 698)  215  215  238 279.7 6.7e-09
sp|P13568|MDR_PLAFF MULTIDRUG RESISTANCE  (1419)  362  223  241 278.3 7.9e-09
sp|P33310|MDL1_YEAST ATP-DEPENDENT PERME  ( 695)  321  211  232 272.7 1.6e-08
sp|P18767|NDVA_RHIME BETA-(1-->2)GLUCAN   ( 616)  305  181  228 268.9 2.6e-08
sp|Q03519|TAP2_HUMAN ANTIGEN PEPTIDE TRA  ( 686)  299  200  227 267.0 3.4e-08
sp|P18768|CHVA_AGRTU BETA-(1-->2)GLUCAN   ( 588)  327  209  225 265.8 4e-08
sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANS  ( 703)  302  184  225 264.5 4.6e-08
sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TR  ( 604)  211  211  217 256.3 1.3e-07
sp|Q03518|TAP1_HUMAN ANTIGEN PEPTIDE TRA  ( 748)  291  163  218 256.0 1.4e-07
sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRA  ( 702)  297  178  217 255.3 1.5e-07
sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANS  ( 725)  320  196  216 253.9 1.8e-07
sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TR  ( 573)  306  180  213 252.0 2.3e-07
sp|P97998|MDL1_CANAL ATP-DEPENDENT PERME  ( 685)  362  200  211 248.5 3.6e-07
sp|P21958|TAP1_MOUSE ANTIGEN PEPTIDE TRA  ( 724)  322  190  210 246.9 4.4e-07
sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TR  ( 634)  189  189  208 245.5 5.3e-07
sp|P16875|MDR1_ENTHI MULTIDRUG RESISTANC  ( 114)  248  159  196 243.3 7e-07
sp|P23858|POTA_ECOLI SPERMIDINE/PUTRESCI  ( 378)  198  166  203 243.3 7.1e-07

>>sp|P21447|MDR3_MOUSE MULTIDRUG RESISTANCE PROTEIN 3 (P  (1276 aa)
 initn: 635 init1: 347 opt: 348 Z-score: 403.0 expect() 8.9e-16
Smith-Waterman score: 597;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     . :::.:::..:.:::::.:::::::::::
sp|P21 QTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLF
        420       430       440       450       460       470      

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       ::::.::::::: :::..:::.:.::.:::::::.::                       
sp|P21 ATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLP-----------------------
        480       490       500       510                          

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            ..:.::::.::.:::::::::::::::::::::::::::::::::.:::..::::
sp|P21 -----HQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAA
                520       530       540       550       560        

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P21 LDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAG
      570       580       590       600       610       620        

>>sp|P06795|MDR1_MOUSE MULTIDRUG RESISTANCE PROTEIN 1 (P  (1276 aa)
 initn: 635 init1: 347 opt: 348 Z-score: 403.0 expect() 8.9e-16
Smith-Waterman score: 597;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     . :::.:::..:.:::::.:::::::::::
sp|P06 QTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLF
     420       430       440       450       460       470         

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       ::::.::::::: :::..:::.:.::.:::::::.::                       
sp|P06 ATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLP-----------------------
     480       490       500       510                             

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            ..:.::::.::.:::::::::::::::::::::::::::::::::.:::..::::
sp|P06 -----HQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAA
             520       530       540       550       560       570 

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P06 LDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTRG
             580       590       600       610       620       630 

>>sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE PROTEIN 2 (P-G  (1278 aa)
 initn: 606 init1: 337 opt: 345 Z-score: 399.6 expect() 1.4e-15
Smith-Waterman score: 575;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     : :::.:::..:.: :::.:::::::::::
sp|Q08 QTVALVGNSGCGKSTTVQLLQRLYDPTEGTISIDGQDIRNFNVRCLREFIGVVSQEPVLF
     420       430       440       450       460       470         

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       .:::.::::::: .::..::..:.::.:::::::.::                       
sp|Q08 STTIAENIRYGRGNVTMDEIKKAVKEANAYDFIMKLP-----------------------
     480       490       500       510                             

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            :::.:::::::.:::::::::::::::::::::::::::::::::.:::. ::::
sp|Q08 -----QKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAA
             520       530       540       550       560       570 

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|Q08 LDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELIKKEGIYFRLVNMQTSG
             580       590       600       610       620       630 

>>sp|P21440|MDR2_MOUSE MULTIDRUG RESISTANCE PROTEIN 2 (P  (1276 aa)
 initn: 607 init1: 337 opt: 343 Z-score: 397.3 expect() 1.9e-15
Smith-Waterman score: 582;  66.452% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     : :::.:::..:.: :::.:::::::::::
sp|P21 QTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLF
     420       430       440       450       460       470         

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       .:::.::::::: .::..:::.:.::.:::::::.::                       
sp|P21 STTIAENIRYGRGNVTMDEIEKAVKEANAYDFIMKLP-----------------------
     480       490       500       510                             

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            :::.:::::::.:::::::::::::::::::::::::::::::::.:::. ::::
sp|P21 -----QKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAA
             520       530       540       550       560       570 

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P21 LDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKEGIYFRLVNMQTAG
             580       590       600       610       620       630 

>>sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P  (1276 aa)
 initn: 605 init1: 341 opt: 342 Z-score: 396.1 expect() 2.2e-15
Smith-Waterman score: 595;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     . :::.:::..:.:::::.:::::::::::
sp|P21 QTVALVGKSGCGKSTTVQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLF
     420       430       440       450       460       470         

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       ::::.::::::: .::..:::.:.::.:::::::.::                       
sp|P21 ATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLP-----------------------
     480       490       500       510                             

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            .::.::::.::.:::::::::::::::::::::::::::::::::.:::..::::
sp|P21 -----HKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAA
             520       530       540       550       560       570 

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P21 LDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYCRLVMMQTRG
             580       590       600       610       620       630 

>>sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P  (1276 aa)
 initn: 605 init1: 341 opt: 342 Z-score: 396.1 expect() 2.2e-15
Smith-Waterman score: 595;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     . :::.:::..:.:::::.:::::::::::
sp|P21 QTVALVGNSGCGKSTTVQLLQRLYDPTEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLF
       420       430       440       450       460       470       

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       ::::.::::::: .::..:::.:.::.:::::::.::                       
sp|P21 ATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLP-----------------------
       480       490       500       510                           

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            .::.::::.::.:::::::::::::::::::::::::::::::::.:::..::::
sp|P21 -----HKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAA
               520       530       540       550       560         

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P21 LDKAREGRTTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELMREKGIYFKLVMTQTAG
     570       580       590       600       610       620         

>>sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-G  (1277 aa)
 initn: 629 init1: 341 opt: 342 Z-score: 396.1 expect() 2.2e-15
Smith-Waterman score: 595;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     . :::.:::..:.:::::.:::::::::::
sp|P43 QTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLF
     420       430       440       450       460       470         

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       ::::.::::::: .::..:::.:.::.:::::::.::                       
sp|P43 ATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLP-----------------------
     480       490       500       510                             

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            .::.::::.::.:::::::::::::::::::::::::::::::::.:::..::::
sp|P43 -----HKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAA
             520       530       540       550       560       570 

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P43 LDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYFKLVMTQTRG
             580       590       600       610       620       630 

>>sp|P21439|MDR3_HUMAN MULTIDRUG RESISTANCE PROTEIN 3 (P  (1279 aa)
 initn: 577 init1: 331 opt: 341 Z-score: 394.9 expect() 2.5e-15
Smith-Waterman score: 556;  63.871% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     : :::.:::..:. ::::.:::::::::::
sp|P21 QTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLF
            430       440       450       460       470       480  

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       .:::.::: ::: .::..::..:.::.:::.:::.::                       
sp|P21 STTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLP-----------------------
            490       500       510                                

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            :::.::::.::.:::::::::::::::::::::::::::::::::.:::. ::::
sp|P21 -----QKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAA
          520       530       540       550       560       570    

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P21 LDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKEGVYFKLVNMQTSG
          580       590       600       610       620       630    

>>sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P  (1281 aa)
 initn: 602 init1: 331 opt: 340 Z-score: 393.7 expect() 2.9e-15
Smith-Waterman score: 580;  65.806% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     : :::.:::..:.:::::.:::::::::::
sp|P23 QTVALVGNSGCGKTTTLQLLQRLYDPTEGTISIDGQDIRNFNVRYLREIIGVVSQEPVLF
            430       440       450       460       470       480  

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       .:::.::::::: .::.:::..:.::.:::.:::.::                       
sp|P23 STTIAENIRYGRGNVTMEEIKKAVKEANAYEFIMKLP-----------------------
            490       500       510                                

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            :::.::::.::.:::::::::::::::::::::::::::::::::.:::. ::::
sp|P23 -----QKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAA
          520       530       540       550       560       570    

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P23 LDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMQKEGVYFKLVNMQTSG
          580       590       600       610       620       630    

>>sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P  (1280 aa)
 initn: 596 init1: 332 opt: 337 Z-score: 390.3 expect() 4.6e-15
Smith-Waterman score: 585;  63.871% identity in 155 aa overlap

                                             10        20        30
6255                                 IFIDGHDIRSLNIRYLREMIGVVSQEPVLF
                                     . .::.:::..:.:.:::.:::::::::::
sp|P08 QTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLF
              430       440       450       460       470       480

               40        50        60        70        80        90
6255   ATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIY
       ::::.::::::: .::..:::.:.::.:::::::.::                       
sp|P08 ATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLP-----------------------
              490       500       510                              

              100       110       120       130       140       150
6255   IMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAA
            .::.::::.::.:::::::::::::::::::::::::::::::::.:::..::.:
sp|P08 -----HKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVA
            520       530       540       550       560       570  

              160       170       180       190       200       210
6255   LDKVQTQTRAEMMGNKETLLHCLLVYVSPFMVSGKDSQPTEALPEPPELQIAPTKACSRI
       :::..                                                       
sp|P08 LDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAG
            580       590       600       610       620       630  



211 residues in 1 query   sequences
26840295 residues in 74019 library sequences
 Tcomplib (4 proc)[version 3.2t01  December 31, 1998]
 start: Thu May 27 10:40:46 1999 done: Thu May 27 10:41:03 1999
 Scan time: 28.470 Display time:  0.290

Function used was  FASTA 

[ GCG | w2h | Staden | GeneExplorer ]

Last modified: Sun, 23 May 1999, [email protected]