BLAST Search results

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Blast search for open reading frame 3 (17772-18374)

GeneQuiz Result at EBI server
BLASTP 2.0.6 [Sept-16-1998]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 17772               17772..18374
         (201 letters)

Database: swissprot36
           74,019 sequences; 26,840,295 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

sp|P06795|MDR1_MOUSE MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...   192  5e-49
sp|P21447|MDR3_MOUSE MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT...   192  5e-49
sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROT...   191  6e-49
sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEI...   191  6e-49
sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...   191  6e-49
sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...   188  7e-48
sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT...   186  2e-47
sp|P21440|MDR2_MOUSE MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROT...   186  2e-47
sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEI...   184  8e-47
sp|P21439|MDR3_HUMAN MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT...   180  2e-45
sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...   148  7e-36
sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 50 (P-...   146  2e-35
sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESISTANCE PROTEIN PMD1.            139  4e-33
sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-...   139  4e-33
sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT...   137  1e-32
sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...   127  1e-29
sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEI...   117  2e-26
sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...   116  4e-26
sp|P13568|MDR_PLAFF MULTIDRUG RESISTANCE PROTEIN (CHLOROQUINE RE...   114  1e-25
sp|P22638|HEPA_ANASP HETEROCYST DIFFERENTIATION ATP-BINDING PROT...   113  2e-25
sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA.     110  2e-24
sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERANCE PROTEIN PRECURSOR.         109  3e-24
sp|P33311|MDL2_YEAST ATP-DEPENDENT PERMEASE MDL2.                     109  5e-24
sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA.     108  6e-24
sp|P55122|HLYB_PASSP LEUKOTOXIN SECRETION ATP-BINDING PROTEIN.        107  1e-23
sp|P97998|MDL1_CANAL ATP-DEPENDENT PERMEASE MDL1.                     107  2e-23
sp|P16532|HLYB_PASHA LEUKOTOXIN SECRETION ATP-BINDING PROTEIN.        106  4e-23
sp|P10089|HLY2_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, CH...   104  9e-23
sp|P08716|HLYB_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, PL...   104  9e-23
sp|P23702|HLYB_ACTAC LEUKOTOXIN SECRETION ATP-BINDING PROTEIN.        104  9e-23
sp|Q57180|YA51_HAEIN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...   104  9e-23
sp|P40416|ATM1_YEAST MITOCHONDRIAL TRANSPORTER ATM1 PRECURSOR.        104  1e-22
sp|P11599|HLYB_PROVU HEMOLYSIN SECRETION ATP-BINDING PROTEIN.         104  2e-22
sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...   103  2e-22
sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...   102  3e-22
sp|P18770|CYAB_BORPE CYCLOLYSIN SECRETION ATP-BINDING PROTEIN CYAB.   102  3e-22
sp|P26760|RT1B_ACTPL RTX-I TOXIN DETERMINANT B (TOXIN RTX-I SECR...   102  3e-22
sp|Q04473|RT3B_ACTPL RTX-III TOXIN DETERMINANT B (TOXIN RTX-III ...   102  3e-22
sp|P33310|MDL1_YEAST ATP-DEPENDENT PERMEASE MDL1.                     102  4e-22
sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1).              100  2e-21
sp|P47261|Y015_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    99  4e-21
sp|P18767|NDVA_RHIME BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTE...    98  1e-20
sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    98  1e-20
sp|P21958|TAP1_MOUSE ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (HISTO...    98  2e-20
sp|P18768|CHVA_AGRTU BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTE...    97  3e-20
sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANSPORTER 2 (APT2).               96  4e-20
sp|Q03518|TAP1_HUMAN ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (PEPTI...    95  8e-20
sp|P22520|CVAB_ECOLI COLICIN V SECRETION ATP-BINDING PROTEIN CVAB.     94  1e-19
sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (HISTO...    94  1e-19
sp|P54683|TAGB_DICDI PRESTALK-SPECIFIC PROTEIN TAGB PRECURSOR (E...    91  1e-18
sp|Q03519|TAP2_HUMAN ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (PEPTI...    90  2e-18
sp|Q57538|Y664_HAEIN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    88  1e-17
sp|P30751|MDL_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEI...    88  1e-17
sp|Q23868|TAGC_DICDI PRESTALK-SPECIFIC PROTEIN TAGC PRECURSOR (E...    88  1e-17
sp|Q11047|Y08A_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    87  2e-17
sp|Q11019|Y07D_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    84  1e-16
sp|P12866|STE6_YEAST MATING FACTOR A SECRETION PROTEIN STE6 (MUL...    84  1e-16
sp|P16877|MDR4_ENTHI MULTIDRUG RESISTANCE PROTEIN 4 (P-GLYCOPROT...    80  3e-15
sp|P47260|Y014_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    80  4e-15
sp|Q11018|Y07C_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    78  1e-14
sp|P16876|MDR3_ENTHI MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT...    78  1e-14
sp|P75095|Y014_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    78  1e-14
sp|P16875|MDR1_ENTHI MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...    77  2e-14
sp|Q11046|Y089_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    76  4e-14
sp|P45082|CYDD_HAEIN TRANSPORT ATP-BINDING PROTEIN CYDD.               76  6e-14
sp|Q03024|APRD_PSEAE ALKALINE PROTEASE SECRETION ATP-BINDING PRO...    75  1e-13
sp|P38735|YHD5_YEAST PROBABLE ATP-DEPENDENT PERMEASE YHL035C.          74  2e-13
sp|P94367|CYDD_BACSU TRANSPORT ATP-BINDING PROTEIN CYDD.               73  5e-13
sp|P29018|CYDD_ECOLI TRANSPORT ATP-BINDING PROTEIN CYDD.               72  6e-13
sp|P33527|MRP1_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1.        71  2e-12
sp|P23596|PRTD_ERWCH PROTEASES SECRETION ATP-BINDING PROTEIN PRTD.     69  4e-12
sp|Q92887|MRP2_HUMAN CANALICULAR MULTISPECIFIC ORGANIC ANION TRA...    69  5e-12
sp|O15440|MRP5_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 (...    69  5e-12
sp|P36497|PEDD_PEDAC PEDIOCIN PA-1 TRANSPORT ATP-BINDING PROTEIN...    69  7e-12
sp|P14772|YL15_YEAST PROBABLE ATP-DEPENDENT TRANSPORTER YLL015W.       67  2e-11
sp|P53706|HST6_CANAL ATP-DEPENDENT PERMEASE HST6 (STE6 HOMOLOG).       66  4e-11
sp|O15438|MRP3_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 3 (...    65  1e-10
sp|P53049|YOR1_YEAST OLIGOMYCIN RESISTANCE ATP-DEPENDENT PERMEAS...    64  2e-10
sp|Q10185|YAWB_SCHPO PROBABLE ATP-DEPENDENT PERMEASE C3F10.11C.        63  3e-10
sp|P45171|POTA_HAEIN SPERMIDINE/PUTRESCINE TRANSPORT ATP-BINDING...    62  9e-10
sp|P33116|SPAT_BACSU SUBTILIN TRANSPORT ATP-BINDING PROTEIN SPAT.      61  2e-09
sp|Q57213|YE74_HAEIN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    61  2e-09
sp|P54537|YQIZ_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BIN...    60  3e-09
sp|P74548|CYSA_SYNY3 SULFATE TRANSPORT ATP-BINDING PROTEIN CYSA.       60  4e-09
sp|P30750|ABC_ECOLI ATP-BINDING PROTEIN ABC.                           57  2e-08
sp|P23858|POTA_ECOLI SPERMIDINE/PUTRESCINE TRANSPORT ATP-BINDING...    57  3e-08
sp|P77795|YDCT_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    57  3e-08
sp|P39109|YCFI_YEAST METAL RESISTANCE PROTEIN YCF1 (YEAST CADMIU...    56  5e-08
sp|P75059|POTA_MYCPN SPERMIDINE/PUTRESCINE TRANSPORT ATP-BINDING...    55  7e-08
sp|P44785|ABC_HAEIN ATP-BINDING PROTEIN ABC.                           55  9e-08
sp|Q58206|Y796_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    55  9e-08
sp|P27675|GLNQ_BACST GLUTAMINE TRANSPORT ATP-BINDING PROTEIN GLNQ.     55  1e-07
sp|P75957|YCFV_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    55  1e-07
sp|P15031|FECE_ECOLI IRON(III) DICITRATE TRANSPORT ATP-BINDING P...    54  2e-07
sp|Q47538|TAUB_ECOLI TAURINE TRANSPORT ATP-BINDING PROTEIN TAUB.       54  2e-07
sp|Q57855|Y412_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    54  2e-07
sp|P47705|Y467_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    54  2e-07
sp|P75110|Y467_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    54  2e-07
sp|P21441|MDR_LEITA MULTIDRUG RESISTANCE PROTEIN (P-GLYCOPROTEIN).     54  2e-07
sp|Q52666|BZTD_RHOCA GLUTAMATE/GLUTAMINE/ASPARTATE/ASPARAGINE TR...    53  3e-07

>sp|P06795|MDR1_MOUSE MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
           Length = 1276
           
 Score =  192 bits (482), Expect = 5e-49
 Identities = 103/155 (66%), Positives = 115/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDG DIR++N+RYLRE+IGVVSQEPVLFATTI ENIRYGR DVT +EIE+A KE+NAY
Sbjct: 450 VSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAY 509

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                             +F+TLVG+RG QLSGGQKQRIAIA
Sbjct: 510 DFIMKLP----------------------------HQFDTLVGERGAQLSGGQKQRIAIA 541

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE +VQAALDK +
Sbjct: 542 RALVRNPKILLLDEATSALDTESEAVVQAALDKAR 576


 Score =  149 bits (372), Expect = 4e-36
 Identities = 86/162 (53%), Positives = 105/162 (64%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            VF+DG +I+ LN+++LR  +G+VSQEP+LF  +I ENI YG     V+ EEI RA KE+N
Sbjct: 1092 VFLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRAVSHEEIVRAAKEAN 1151

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI +LPD                            K+ T VGD+GTQLSGGQKQRIA
Sbjct: 1152 IHQFIDSLPD----------------------------KYNTRVGDKGTQLSGGQKQRIA 1183

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARALVR P ILLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1184 IARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1225


>sp|P21447|MDR3_MOUSE MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3) (MDR1A).
           Length = 1276
           
 Score =  192 bits (482), Expect = 5e-49
 Identities = 103/155 (66%), Positives = 115/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDG DIR++N+RYLRE+IGVVSQEPVLFATTI ENIRYGR DVT +EIE+A KE+NAY
Sbjct: 447 VSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAY 506

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                             +F+TLVG+RG QLSGGQKQRIAIA
Sbjct: 507 DFIMKLP----------------------------HQFDTLVGERGAQLSGGQKQRIAIA 538

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE +VQAALDK +
Sbjct: 539 RALVRNPKILLLDEATSALDTESEAVVQAALDKAR 573


 Score =  149 bits (373), Expect = 3e-36
 Identities = 86/162 (53%), Positives = 105/162 (64%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            VF+DG +I+ LN+++LR  +G+VSQEP+LF  +I ENI YG     V+ EEI RA KE+N
Sbjct: 1090 VFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEAN 1149

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI +LPD                            K+ T VGD+GTQLSGGQKQRIA
Sbjct: 1150 IHQFIDSLPD----------------------------KYNTRVGDKGTQLSGGQKQRIA 1181

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARALVR P ILLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1182 IARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1223


>sp|P21449|MDR2_CRIGR MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2).
           Length = 1276
           
 Score =  191 bits (481), Expect = 6e-49
 Identities = 103/155 (66%), Positives = 115/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDG DIR++N+RYLRE+IGVVSQEPVLFATTI ENIRYGR +VT +EIE+A KE+NAY
Sbjct: 450 VSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAY 509

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                             KF+TLVG+RG QLSGGQKQRIAIA
Sbjct: 510 DFIMKLP----------------------------HKFDTLVGERGAQLSGGQKQRIAIA 541

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE +VQAALDK +
Sbjct: 542 RALVRNPKILLLDEATSALDTESEAVVQAALDKAR 576


 Score =  153 bits (382), Expect = 3e-37
 Identities = 87/162 (53%), Positives = 107/162 (65%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            VF+DG +I+ LN+++LR  +G+VSQEP+LF  +I ENI YG     V+Q+EIERA KE+N
Sbjct: 1092 VFLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEAN 1151

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI +LPD                            K+ T VGD+GTQLSGGQKQRIA
Sbjct: 1152 IHQFIESLPD----------------------------KYNTRVGDKGTQLSGGQKQRIA 1183

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARALVR P ILLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1184 IARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1225


>sp|P43245|MDR1_RAT MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
           Length = 1277
           
 Score =  191 bits (481), Expect = 6e-49
 Identities = 103/155 (66%), Positives = 115/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDG DIR++N+RYLRE+IGVVSQEPVLFATTI ENIRYGR +VT +EIE+A KE+NAY
Sbjct: 450 VSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAY 509

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                             KF+TLVG+RG QLSGGQKQRIAIA
Sbjct: 510 DFIMKLP----------------------------HKFDTLVGERGAQLSGGQKQRIAIA 541

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE +VQAALDK +
Sbjct: 542 RALVRNPKILLLDEATSALDTESEAVVQAALDKAR 576


 Score =  140 bits (349), Expect = 2e-33
 Identities = 90/185 (48%), Positives = 112/185 (59%), Gaps = 35/185 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            VF+DG +I+ LN++ +R + G+VSQEP+LF  +I ENI YG     V+ EEI RA +E+N
Sbjct: 1094 VFLDGKEIKQLNVQCVRAL-GIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREAN 1152

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI +LP+                            K+ T VGD+GTQLSGGQKQRIA
Sbjct: 1153 IHQFIDSLPE----------------------------KYNTRVGDKGTQLSGGQKQRIA 1184

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTCSPSPCR---TQPLDLKDI 174
            IARALVR P ILLLDEATSALD ESE +VQ ALDK  + +TC     R    Q  DL  +
Sbjct: 1185 IARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADLIVV 1244

Query: 175  SQYGQ 179
             Q GQ
Sbjct: 1245 IQNGQ 1249


>sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
           Length = 1276
           
 Score =  191 bits (481), Expect = 6e-49
 Identities = 103/155 (66%), Positives = 115/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDG DIR++N+RYLRE+IGVVSQEPVLFATTI ENIRYGR +VT +EIE+A KE+NAY
Sbjct: 448 VSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAY 507

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                             KF+TLVG+RG QLSGGQKQRIAIA
Sbjct: 508 DFIMKLP----------------------------HKFDTLVGERGAQLSGGQKQRIAIA 539

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE +VQAALDK +
Sbjct: 540 RALVRNPKILLLDEATSALDTESEAVVQAALDKAR 574


 Score =  152 bits (379), Expect = 6e-37
 Identities = 86/162 (53%), Positives = 106/162 (65%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            VF+DG ++  LN+++LR  +G+VSQEP+LF  +I ENI YG     V+Q+EIERA KE+N
Sbjct: 1091 VFLDGKEVNQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAKEAN 1150

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI +LPD                            K+ T VGD+GTQLSGGQKQRIA
Sbjct: 1151 IHQFIESLPD----------------------------KYNTRVGDKGTQLSGGQKQRIA 1182

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARALVR P ILLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1183 IARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1224


>sp|P08183|MDR1_HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
           Length = 1280
           
 Score =  188 bits (472), Expect = 7e-48
 Identities = 100/155 (64%), Positives = 114/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V +DG DIR++N+R+LRE+IGVVSQEPVLFATTI ENIRYGR +VT +EIE+A KE+NAY
Sbjct: 451 VSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAY 510

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                             KF+TLVG+RG QLSGGQKQRIAIA
Sbjct: 511 DFIMKLP----------------------------HKFDTLVGERGAQLSGGQKQRIAIA 542

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE +VQ ALDK +
Sbjct: 543 RALVRNPKILLLDEATSALDTESEAVVQVALDKAR 577


 Score =  146 bits (364), Expect = 3e-35
 Identities = 85/162 (52%), Positives = 105/162 (64%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            V +DG +I+ LN+++LR  +G+VSQEP+LF  +I ENI YG     V+QEEI RA KE+N
Sbjct: 1094 VLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEAN 1153

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI +LP+                            K+ T VGD+GTQLSGGQKQRIA
Sbjct: 1154 IHAFIESLPN----------------------------KYSTKVGDKGTQLSGGQKQRIA 1185

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARALVR P ILLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1186 IARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTC 1227


>sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3).
           Length = 1281
           
 Score =  186 bits (468), Expect = 2e-47
 Identities = 101/155 (65%), Positives = 114/155 (73%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DIR+ N+RYLRE+IGVVSQEPVLF+TTI ENIRYGR +VT EEI++A KE+NAY
Sbjct: 453 ISIDGQDIRNFNVRYLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMEEIKKAVKEANAY 512

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           +FIM LP                            QKF+TLVG+RG QLSGGQKQRIAIA
Sbjct: 513 EFIMKLP----------------------------QKFDTLVGERGAQLSGGQKQRIAIA 544

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE  VQAALDK +
Sbjct: 545 RALVRNPKILLLDEATSALDTESEAEVQAALDKAR 579


 Score =  142 bits (355), Expect = 4e-34
 Identities = 81/162 (50%), Positives = 103/162 (63%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            V +DG + + LNI++LR  +G+VSQEPVLF  +I ENI YG     V+Q+EI RA K +N
Sbjct: 1095 VLLDGQEAKKLNIQWLRAQLGIVSQEPVLFDCSIAENIAYGDNSRVVSQDEIVRAAKAAN 1154

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI  LP                            QK++T VGD+GTQLSGGQKQR+A
Sbjct: 1155 IHPFIETLP----------------------------QKYKTRVGDKGTQLSGGQKQRLA 1186

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            I RAL+R P++LLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1187 IRRALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTC 1228


>sp|P21440|MDR2_MOUSE MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2).
           Length = 1276
           
 Score =  186 bits (468), Expect = 2e-47
 Identities = 102/155 (65%), Positives = 113/155 (72%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DIR+ N+R LRE+IGVVSQEPVLF+TTI ENIRYGR +VT +EIE+A KE+NAY
Sbjct: 450 ISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIEKAVKEANAY 509

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                            QKF+TLVGDRG QLSGGQKQRIAIA
Sbjct: 510 DFIMKLP----------------------------QKFDTLVGDRGAQLSGGQKQRIAIA 541

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE  VQAALDK +
Sbjct: 542 RALVRNPKILLLDEATSALDTESEAEVQAALDKAR 576


 Score =  143 bits (358), Expect = 2e-34
 Identities = 81/162 (50%), Positives = 102/162 (62%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            V +DG + + LN+++LR  +G+VSQEP+LF  +I ENI YG     V  +EI RA KE+N
Sbjct: 1090 VLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVPHDEIVRAAKEAN 1149

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI  LP                            QK+ T VGD+GTQLSGGQKQRIA
Sbjct: 1150 IHPFIETLP----------------------------QKYNTRVGDKGTQLSGGQKQRIA 1181

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARAL+R P++LLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1182 IARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTC 1223


>sp|Q08201|MDR2_RAT MULTIDRUG RESISTANCE PROTEIN 2 (P-GLYCOPROTEIN 2).
           Length = 1278
           
 Score =  184 bits (463), Expect = 8e-47
 Identities = 101/155 (65%), Positives = 112/155 (72%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DIR+ N+R LRE IGVVSQEPVLF+TTI ENIRYGR +VT +EI++A KE+NAY
Sbjct: 450 ISIDGQDIRNFNVRCLREFIGVVSQEPVLFSTTIAENIRYGRGNVTMDEIKKAVKEANAY 509

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                            QKF+TLVGDRG QLSGGQKQRIAIA
Sbjct: 510 DFIMKLP----------------------------QKFDTLVGDRGAQLSGGQKQRIAIA 541

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RALVRNPKILLLDEATSALD ESE  VQAALDK +
Sbjct: 542 RALVRNPKILLLDEATSALDTESEAEVQAALDKAR 576


 Score =  146 bits (366), Expect = 2e-35
 Identities = 82/162 (50%), Positives = 105/162 (64%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            V +DG + + LN+++LR  +G+VSQEP+LF  +I +NI YG     V+Q+EI RA KE+N
Sbjct: 1092 VLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAKNIAYGDNSRVVSQDEIVRAAKEAN 1151

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI  LP                            QK+ET VGD+GTQLSGGQKQRIA
Sbjct: 1152 IHPFIETLP----------------------------QKYETRVGDKGTQLSGGQKQRIA 1183

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARAL+R P++LLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1184 IARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTC 1225


>sp|P21439|MDR3_HUMAN MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3).
           Length = 1279
           
 Score =  180 bits (451), Expect = 2e-45
 Identities = 98/153 (64%), Positives = 111/153 (72%), Gaps = 28/153 (18%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           IDG DIR+ N+ YLRE+IGVVSQEPVLF+TTI ENI YGR +VT +EI++A KE+NAY+F
Sbjct: 455 IDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEF 514

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
           IM LP                            QKF+TLVG+RG QLSGGQKQRIAIARA
Sbjct: 515 IMKLP----------------------------QKFDTLVGERGAQLSGGQKQRIAIARA 546

Query: 123 LVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           LVRNPKILLLDEATSALD ESE  VQAALDK +
Sbjct: 547 LVRNPKILLLDEATSALDTESEAEVQAALDKAR 579


 Score =  141 bits (353), Expect = 6e-34
 Identities = 81/162 (50%), Positives = 102/162 (62%), Gaps = 31/162 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD--VTQEEIERATKESN 58
            V +DG + + LN+++LR  +G+VSQEP+LF  +I ENI YG     V+Q+EI  A K +N
Sbjct: 1093 VLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAAN 1152

Query: 59   AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIA 118
             + FI  LP                             K+ET VGD+GTQLSGGQKQRIA
Sbjct: 1153 IHPFIETLP----------------------------HKYETRVGDKGTQLSGGQKQRIA 1184

Query: 119  IARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            IARAL+R P+ILLLDEATSALD ESE +VQ ALDK  + +TC
Sbjct: 1185 IARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTC 1226


>sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN A).
           Length = 1321
           
 Score =  148 bits (370), Expect = 7e-36
 Identities = 85/153 (55%), Positives = 99/153 (64%), Gaps = 28/153 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG D+R +N+ +LR+ + VVSQEP LF  TI ENI  G+  +T+EE+  A K +NA 
Sbjct: 475 ITIDGVDVRDINLEFLRKNVAVVSQEPALFNCTIEENISLGKEGITREEMVAACKMANAE 534

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            FI  LP+                             + TLVGDRGTQLSGGQKQRIAIA
Sbjct: 535 KFIKTLPN----------------------------GYNTLVGDRGTQLSGGQKQRIAIA 566

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDK 153
           RALVRNPKILLLDEATSALDAESE IVQ ALDK
Sbjct: 567 RALVRNPKILLLDEATSALDAESEGIVQQALDK 599


 Score =  142 bits (354), Expect = 5e-34
 Identities = 85/163 (52%), Positives = 103/163 (63%), Gaps = 33/163 (20%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD---VTQEEIERATKES 57
            +FIDG +I++LN  + R  I +VSQEP LF  +I ENI YG LD   VT  ++E A + +
Sbjct: 1136 IFIDGSEIKTLNPEHTRSQIAIVSQEPTLFDCSIAENIIYG-LDPSSVTMAQVEEAARLA 1194

Query: 58   NAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
            N ++FI  LP+                             FET VGDRGTQLSGGQKQRI
Sbjct: 1195 NIHNFIAELPE----------------------------GFETRVGDRGTQLSGGQKQRI 1226

Query: 118  AIARALVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTC 159
            AIARALVRNPKILLLDEATSALD ESE +VQ ALD+  + +TC
Sbjct: 1227 AIARALVRNPKILLLDEATSALDTESEKVVQEALDRAREGRTC 1269


>sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 50 (P-GLYCOPROTEIN 50).
           Length = 1302
           
 Score =  146 bits (366), Expect = 2e-35
 Identities = 80/152 (52%), Positives = 100/152 (65%), Gaps = 28/152 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V +DG D+R+LN+ +LR  IGVV QEPVLFATTI ENIRYGR   TQ +IE+A + +N +
Sbjct: 461 VKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAANCH 520

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  LP                            + ++T VG++G Q+SGGQKQRIAIA
Sbjct: 521 DFITRLP----------------------------KGYDTQVGEKGAQISGGQKQRIAIA 552

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALD 152
           RALVR P++LLLDEATSALD  SE  VQ+AL+
Sbjct: 553 RALVRQPQVLLLDEATSALDPTSEKRVQSALE 584


 Score =  120 bits (299), Expect = 1e-27
 Identities = 76/148 (51%), Positives = 94/148 (63%), Gaps = 33/148 (22%)

Query: 16   LREMIGVVSQEPVLFATTITENIRYG---RLDVTQEEIERATKESNAYDFIMNLPDVRPH 72
            LR  +G+VSQEPVLF  TI ENI YG   R DV+ +EI  A K+SN ++FI  LP     
Sbjct: 1133 LRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALP----- 1187

Query: 73   LWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLL 132
                                   Q ++T +G + +QLSGGQKQRIAIARALVRNPKIL+L
Sbjct: 1188 -----------------------QGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILIL 1223

Query: 133  DEATSALDAESETIVQAALDKVQT-QTC 159
            DEATSALD ESE +VQ ALD+ ++ +TC
Sbjct: 1224 DEATSALDLESEKVVQQALDEARSGRTC 1251


>sp|P36619|PMD1_SCHPO LEPTOMYCIN B RESISTANCE PROTEIN PMD1.
           Length = 1362
           
 Score =  139 bits (346), Expect = 4e-33
 Identities = 82/161 (50%), Positives = 102/161 (62%), Gaps = 37/161 (22%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD-----VTQEEIER--- 52
           VF+DG D+R+LN+  LR  I +V QEPVLFATT+ ENI YG  D     +++EE+ER   
Sbjct: 479 VFLDGKDLRTLNVASLRNQISLVQQEPVLFATTVFENITYGLPDTIKGTLSKEELERRVY 538

Query: 53  -ATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSG 111
            A K +NAYDFIM LP+                            +F T VG RG  +SG
Sbjct: 539 DAAKLANAYDFIMTLPE----------------------------QFSTNVGQRGFLMSG 570

Query: 112 GQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALD 152
           GQKQRIAIARA++ +PKILLLDEATSALD++SE +VQ ALD
Sbjct: 571 GQKQRIAIARAVISDPKILLLDEATSALDSKSEVLVQKALD 611


 Score =  123 bits (306), Expect = 2e-28
 Identities = 71/153 (46%), Positives = 94/153 (61%), Gaps = 29/153 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRL-DVTQEEIERATKESNA 59
            V +DG ++R  NI   R+ I +VSQEP L+  T+ ENI  G   DV++EE+  A K++N 
Sbjct: 1178 VLVDGVNVRDYNINDYRKQIALVSQEPTLYQGTVRENIVLGASKDVSEEEMIEACKKANI 1237

Query: 60   YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
            ++FI+ LP+                             + TL G +G+ LSGGQKQRIAI
Sbjct: 1238 HEFILGLPN----------------------------GYNTLCGQKGSSLSGGQKQRIAI 1269

Query: 120  ARALVRNPKILLLDEATSALDAESETIVQAALD 152
            ARAL+RNPKILLLDEATSALD+ SE +VQ AL+
Sbjct: 1270 ARALIRNPKILLLDEATSALDSHSEKVVQEALN 1302


>sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-GLYCOPROTEIN 65).
           Length = 1302
           
 Score =  139 bits (346), Expect = 4e-33
 Identities = 77/152 (50%), Positives = 97/152 (63%), Gaps = 28/152 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V +D  DIR  NI++LR  I VV QEPVLF  TI +NI YG+   TQ+EIE A  ++ A+
Sbjct: 464 VLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQKEIEAAATQAGAH 523

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           +FI NLP                            + + +++G+RG+QLSGGQKQRIAIA
Sbjct: 524 EFITNLP----------------------------ESYRSMIGERGSQLSGGQKQRIAIA 555

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALD 152
           RAL++NPKILLLDEATSALD +SE  VQ ALD
Sbjct: 556 RALIQNPKILLLDEATSALDYQSEKQVQQALD 587


 Score =  127 bits (315), Expect = 2e-29
 Identities = 87/195 (44%), Positives = 107/195 (54%), Gaps = 43/195 (22%)

Query: 1    VFIDGHDIR-SLNIRYLREMIGVVSQEPVLFATTITENIRYG--RLDVTQEEIERATKES 57
            + ID  DI+  L +  +R  +G+VSQEP LF  +I ENI YG  R  V+  EI  A K +
Sbjct: 1118 IHIDHDDIQHDLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSA 1177

Query: 58   NAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
            NA+ FI++LP+                             ++T +G RGTQLSGGQKQRI
Sbjct: 1178 NAHSFIISLPN----------------------------GYDTRMGARGTQLSGGQKQRI 1209

Query: 118  AIARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCSPSPC--------RTQPL 169
            AIARALVRNPKILLLDEATSALD +SE +VQ ALD      CS   C          Q  
Sbjct: 1210 AIARALVRNPKILLLDEATSALDLQSEQLVQQALD----TACSGRTCIVIAHRLSTVQNA 1265

Query: 170  DLKDISQYGQYVFSG 184
            D+  + Q GQ V  G
Sbjct: 1266 DVICVIQNGQVVEQG 1280


>sp|P34713|MDR3_CAEEL MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN C).
            Length = 1254
            
 Score =  137 bits (342), Expect = 1e-32
 Identities = 78/160 (48%), Positives = 101/160 (62%), Gaps = 29/160 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            V ID  DIR L++++LR+ I +V QEP LF  TI ENI YG  ++TQ+++E+A   +N +
Sbjct: 1074 VKIDDSDIRDLSVKHLRDNIALVGQEPTLFNLTIRENITYGLENITQDQVEKAATLANIH 1133

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
             F+M LPD                             ++T VG  G +LSGGQKQR+AIA
Sbjct: 1134 TFVMGLPD----------------------------GYDTSVGASGGRLSGGQKQRVAIA 1165

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAALDKVQT-QTC 159
            RA+VR+PKILLLDEATSALD ESE IVQ ALDK +  +TC
Sbjct: 1166 RAIVRDPKILLLDEATSALDTESEKIVQEALDKARLGRTC 1205


 Score =  134 bits (335), Expect = 8e-32
 Identities = 72/151 (47%), Positives = 95/151 (62%), Gaps = 28/151 (18%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           +DG  I+  NIR+LR  IG+V QEP++F  T+ ENIR G + +T ++IE A K +NA++F
Sbjct: 437 LDGIPIQEYNIRWLRSTIGIVQQEPIIFVATVAENIRMGDVLITDQDIEEACKMANAHEF 496

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
           I  L D                            +++T++G    QLSGGQKQR+AIARA
Sbjct: 497 ICKLSD----------------------------RYDTVIGAGAVQLSGGQKQRVAIARA 528

Query: 123 LVRNPKILLLDEATSALDAESETIVQAALDK 153
           +VR P+ILLLDEATSALD ESE +VQ ALDK
Sbjct: 529 IVRKPQILLLDEATSALDTESERMVQTALDK 559


>sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1).
           Length = 1280
           
 Score =  127 bits (316), Expect = 1e-29
 Identities = 74/154 (48%), Positives = 96/154 (62%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V +DG  +R L +R  R+ IG+VSQEP LFA T+ EN+R G+ + T EE+  A +++N +
Sbjct: 450 VLVDGVRMRELCLREWRDQIGIVSQEPNLFAGTMMENVRMGKPNATDEEVVEACRQANIH 509

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           D IM LPD                            +++T VG  G+ LSGGQKQRIAIA
Sbjct: 510 DTIMALPD----------------------------RYDTPVGPVGSLLSGGQKQRIAIA 541

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV+ P ILLLDEATSALD +SE  VQAALD++
Sbjct: 542 RALVKRPPILLLDEATSALDRKSEMEVQAALDQL 575


 Score =  104 bits (258), Expect = 9e-23
 Identities = 62/157 (39%), Positives = 87/157 (54%), Gaps = 28/157 (17%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + ++G D+ SL+I   R  I +V QEP LF+ T+ ENIRY R   T EE+E A + ++ +
Sbjct: 1095 ISVNGRDLSSLDIAEWRRNISIVLQEPNLFSGTVRENIRYAREGATDEEVEEAARLAHIH 1154

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
              I+   D                             ++T VG +G  LSGGQKQRIAIA
Sbjct: 1155 HEIIKWTD----------------------------GYDTEVGYKGRALSGGQKQRIAIA 1186

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
            R L+R P++LLLDEATSALD+ +E  VQ  ++  Q +
Sbjct: 1187 RGLLRRPRLLLLDEATSALDSVTEAKVQEGIEAFQAK 1223


>sp|P55469|Y4GM_RHISN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEIN Y4GM.
           Length = 586
           
 Score =  117 bits (290), Expect = 2e-26
 Identities = 66/154 (42%), Positives = 90/154 (57%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V +DGHD++ +  R LR+ IG V Q+  LF+ TI  NI  GR   + EEI  A K +NA+
Sbjct: 403 VTVDGHDLKDVTFRSLRDRIGFVGQDTFLFSGTIKYNISLGREGASDEEIIEAAKTANAH 462

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM +P                              ++T VG+ G +LSGGQKQRI IA
Sbjct: 463 DFIMKMP----------------------------HGYDTEVGENGIKLSGGQKQRITIA 494

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RA++RN +IL+ DEATSALD+ESE  ++ AL ++
Sbjct: 495 RAMLRNAEILIFDEATSALDSESEIQIRQALARL 528


>sp|P45861|YWJA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN IN ACDA 5'REGION.
           Length = 575
           
 Score =  116 bits (287), Expect = 4e-26
 Identities = 61/154 (39%), Positives = 92/154 (59%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG  I+ + +  LR  IGVV Q+  LF+ T+ ENI YGRL  ++E+I +A K+++  
Sbjct: 390 ITIDGISIKDMTLSSLRGQIGVVQQDVFLFSGTLRENIAYGRLGASEEDIWQAVKQAHLE 449

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           + + N+PD                              +T++G+RG +LSGGQKQR++IA
Sbjct: 450 ELVHNMPD----------------------------GLDTMIGERGVKLSGGQKQRLSIA 481

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           R  ++NP IL+LDEATSALD E+E  +Q AL ++
Sbjct: 482 RMFLKNPSILILDEATSALDTETEAAIQKALQEL 515


>sp|P13568|MDR_PLAFF MULTIDRUG RESISTANCE PROTEIN (CHLOROQUINE RESISTANCE PROTEIN).
            Length = 1419
            
 Score =  114 bits (282), Expect = 1e-25
 Identities = 64/151 (42%), Positives = 91/151 (59%), Gaps = 28/151 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + +D  +I   N+R LR +  +VSQEP+LF  +I ENI++GR D T E+++R +K +   
Sbjct: 1232 ILLDDINICDYNLRDLRNLFSIVSQEPMLFNMSIYENIKFGREDATLEDVKRVSKFAAID 1291

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            +FI +LP+                            K++T VG  G  LSGGQKQRIAIA
Sbjct: 1292 EFIESLPN----------------------------KYDTNVGPYGKSLSGGQKQRIAIA 1323

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAAL 151
            RAL+R PKILLLDEATS+LD+ SE +++  +
Sbjct: 1324 RALLREPKILLLDEATSSLDSNSEKLIEKTI 1354


 Score =  106 bits (262), Expect = 3e-23
 Identities = 62/169 (36%), Positives = 98/169 (57%), Gaps = 17/169 (10%)

Query: 4   DGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQ--------EEIERATK 55
           D H+++ +N+++ R  IGVVSQ+P+LF+ +I  NI+Y    +          EE    T 
Sbjct: 441 DSHNLKDINLKWWRSKIGVVSQDPLLFSNSIKNNIKYSLYSLKDLEAMENYYEENTNDTY 500

Query: 56  ESNAYDFIMN-------LPDVRPHLWLPYLSLAPSRSNANIYIMISE--QKFETLVGDRG 106
           E+  +  I N       L   + +  +    +        I+  +S    K++TLVG   
Sbjct: 501 ENKNFSLISNSMTSNELLEMKKEYQTIKDSDVVDVSKKVLIHDFVSSLPDKYDTLVGSNA 560

Query: 107 TQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           ++LSGGQKQRI+IARA++RNPKIL+LDEATS+LD +SE +VQ  ++ ++
Sbjct: 561 SKLSGGQKQRISIARAIMRNPKILILDEATSSLDNKSEYLVQKTINNLK 609


>sp|P22638|HEPA_ANASP HETEROCYST DIFFERENTIATION ATP-BINDING PROTEIN HEPA.
           Length = 532
           
 Score =  113 bits (280), Expect = 2e-25
 Identities = 61/154 (39%), Positives = 91/154 (58%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + +DG D++   I  LR  + VVSQ+  +F T+I +NI YG    ++ EI    + +NA 
Sbjct: 346 ILVDGLDVQYFEINSLRRKMAVVSQDTFIFNTSIRDNIAYGTSGASEAEIREVARLANAL 405

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            FI  +P+                             F+T +GDRG +LSGGQ+QRIAIA
Sbjct: 406 QFIEEMPE----------------------------GFDTKLGDRGVRLSGGQRQRIAIA 437

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RAL+R+P+IL+LDEATSALD+ SE ++Q +++K+
Sbjct: 438 RALLRDPEILILDEATSALDSVSERLIQESIEKL 471


>sp|P27299|MSBA_ECOLI PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA.
           Length = 582
           
 Score =  110 bits (273), Expect = 2e-24
 Identities = 64/161 (39%), Positives = 90/161 (55%), Gaps = 29/161 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD-VTQEEIERATKESNA 59
           + +DGHD+R   +  LR  + +VSQ   LF  T+  NI Y R +  ++E+IE A + + A
Sbjct: 400 ILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYA 459

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
            DFI  +                            +   +T++G+ G  LSGGQ+QRIAI
Sbjct: 460 MDFINKM----------------------------DNGLDTVIGENGVLLSGGQRQRIAI 491

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           ARAL+R+  IL+LDEATSALD ESE  +QAALD++Q    S
Sbjct: 492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTS 532


>sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERANCE PROTEIN PRECURSOR.
           Length = 830
           
 Score =  109 bits (271), Expect = 3e-24
 Identities = 61/154 (39%), Positives = 88/154 (56%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + ID  DIR++ +  LR  IGVV Q+  LF  TI  NI+Y +   T EEI  A K +  +
Sbjct: 641 ITIDDQDIRNVTLSSLRSSIGVVPQDSTLFNDTILYNIKYAKPSATNEEIYAAAKAAQIH 700

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           D I+  PD                             + + VG+RG +LSGG+KQR+A+A
Sbjct: 701 DRILQFPD----------------------------GYNSRVGERGLKLSGGEKQRVAVA 732

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RA++++P I+LLDEATSALD  +E  +QAAL+++
Sbjct: 733 RAILKDPSIILLDEATSALDTNTERQIQAALNRL 766


>sp|P33311|MDL2_YEAST ATP-DEPENDENT PERMEASE MDL2.
           Length = 820
           
 Score =  109 bits (269), Expect = 5e-24
 Identities = 64/145 (44%), Positives = 81/145 (55%), Gaps = 29/145 (20%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYG-RLDVTQEEIERATKESNA 59
           + ID  DI  LN + LR  IG+V QEPVL + TI +NI YG     T+EEI    K+   
Sbjct: 552 ITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFC 611

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
           ++FI   P+                             ++T++G  GT LSGGQKQRIAI
Sbjct: 612 HNFITKFPNT----------------------------YDTVIGPHGTLLSGGQKQRIAI 643

Query: 120 ARALVRNPKILLLDEATSALDAESE 144
           ARAL++ P IL+LDEATSALD ESE
Sbjct: 644 ARALIKKPTILILDEATSALDVESE 668


>sp|P44407|MSBA_HAEIN PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA.
           Length = 587
           
 Score =  108 bits (268), Expect = 6e-24
 Identities = 65/156 (41%), Positives = 90/156 (57%), Gaps = 29/156 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD-VTQEEIERATKESNA 59
           + +DG +I+   +  LRE   VVSQ+  LF  TI  NI Y   D  ++EEI  A K + A
Sbjct: 405 ILLDGVNIQDYRLSNLRENCAVVSQQVHLFNDTIANNIAYAAQDKYSREEIIAAAKAAYA 464

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
            +FI  LP V                            F+T++G+ GT LSGGQ+QR+AI
Sbjct: 465 LEFIEKLPQV----------------------------FDTVIGENGTSLSGGQRQRLAI 496

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           ARAL+RN  +L+LDEATSALD ESE  +Q+AL++++
Sbjct: 497 ARALLRNSPVLILDEATSALDTESERAIQSALEELK 532


>sp|P55122|HLYB_PASSP LEUKOTOXIN SECRETION ATP-BINDING PROTEIN.
           Length = 708
           
 Score =  107 bits (265), Expect = 1e-23
 Identities = 66/154 (42%), Positives = 86/154 (54%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  IGVV Q+ VL   +I ENI      ++ E +  A K + A+
Sbjct: 527 VLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRENIALSEPGMSMERVIYAAKLAGAH 586

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI    DVR                         + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 587 DFIS---DVR-------------------------EGYNTIVGEQGAGLSGGQRQRIAIA 618

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NPKIL+ DEATSALD ESE I+   + K+
Sbjct: 619 RALVNNPKILIFDEATSALDYESEHIIMQNMQKI 652


>sp|P97998|MDL1_CANAL ATP-DEPENDENT PERMEASE MDL1.
           Length = 685
           
 Score =  107 bits (264), Expect = 2e-23
 Identities = 63/145 (43%), Positives = 83/145 (56%), Gaps = 29/145 (20%)

Query: 8   IRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLP 67
           I  LN+ + R  +G V QEP+LF+ TI ENI +G+ D T EEI  A   S A +F+ +LP
Sbjct: 506 ITDLNLNHYRSKLGYVQQEPLLFSGTIKENILFGKEDATDEEINNALNLSYASNFVRHLP 565

Query: 68  DVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVG-DRGTQLSGGQKQRIAIARALVRN 126
           D                              +T +G    TQLSGGQKQR+++AR L+R+
Sbjct: 566 D----------------------------GLDTKIGASNSTQLSGGQKQRVSLARTLIRD 597

Query: 127 PKILLLDEATSALDAESETIVQAAL 151
           PKIL+LDEATSALD+ SE IV + L
Sbjct: 598 PKILILDEATSALDSVSEEIVMSNL 622


>sp|P16532|HLYB_PASHA LEUKOTOXIN SECRETION ATP-BINDING PROTEIN.
           Length = 708
           
 Score =  106 bits (261), Expect = 4e-23
 Identities = 64/154 (41%), Positives = 83/154 (53%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  IGVV Q+ VL   +I ENI      +  E +  A K + A+
Sbjct: 527 VLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAH 586

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  L                             + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 587 DFISEL----------------------------REGYNTIVGEQGAGLSGGQRQRIAIA 618

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NPKIL+ DEATSALD ESE I+   + K+
Sbjct: 619 RALVNNPKILIFDEATSALDYESEHIIMQNMQKI 652


>sp|P10089|HLY2_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, CHROMOSOMAL.
           Length = 707
           
 Score =  104 bits (258), Expect = 9e-23
 Identities = 61/154 (39%), Positives = 85/154 (54%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  +GVV Q+ VL   +I +NI      ++ E++  A K + A+
Sbjct: 526 VLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAH 585

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  L                             + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 586 DFISEL----------------------------REGYNTIVGEQGAGLSGGQRQRIAIA 617

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NPKIL+ DEATSALD ESE ++   + K+
Sbjct: 618 RALVNNPKILIFDEATSALDYESEHVIMRNMHKI 651


>sp|P08716|HLYB_ECOLI HEMOLYSIN SECRETION ATP-BINDING PROTEIN, PLASMID.
           Length = 707
           
 Score =  104 bits (258), Expect = 9e-23
 Identities = 61/154 (39%), Positives = 85/154 (54%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  +GVV Q+ VL   +I +NI      ++ E++  A K + A+
Sbjct: 526 VLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAH 585

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  L                             + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 586 DFISEL----------------------------REGYNTIVGEQGAGLSGGQRQRIAIA 617

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NPKIL+ DEATSALD ESE ++   + K+
Sbjct: 618 RALVNNPKILIFDEATSALDYESEHVIMRNMHKI 651


>sp|P23702|HLYB_ACTAC LEUKOTOXIN SECRETION ATP-BINDING PROTEIN.
           Length = 707
           
 Score =  104 bits (258), Expect = 9e-23
 Identities = 62/154 (40%), Positives = 84/154 (54%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  +GVV Q+ VL   +I ENI      +  E++  A K + A+
Sbjct: 526 VLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIRENIALTNPGMPMEKVIAAAKLAGAH 585

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  L                             + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 586 DFISEL----------------------------REGYNTVVGEQGAGLSGGQRQRIAIA 617

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NP+IL+ DEATSALD ESE I+   + K+
Sbjct: 618 RALVNNPRILIFDEATSALDYESENIIMHNMHKI 651


>sp|Q57180|YA51_HAEIN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN HI1051.
           Length = 614
           
 Score =  104 bits (258), Expect = 9e-23
 Identities = 61/154 (39%), Positives = 91/154 (58%), Gaps = 23/154 (14%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG ++ ++    LR  IG+V+Q+  L   ++ +NI YGR + T EE+  A + + A 
Sbjct: 421 ITIDGQNVLNVQQESLRRQIGLVTQDTSLLHRSVRDNIIYGRPNATDEEMVLAAERAEAA 480

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI            P+LS +  R             ++  VG+RG +LSGGQ+QRIAIA
Sbjct: 481 DFI------------PFLSDSQGRKG-----------YDAHVGERGVKLSGGQRQRIAIA 517

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           R ++++  ILLLDEATSALD+E E  +Q +LDK+
Sbjct: 518 RVMLKDAPILLLDEATSALDSEVEVAIQESLDKM 551


>sp|P40416|ATM1_YEAST MITOCHONDRIAL TRANSPORTER ATM1 PRECURSOR.
           Length = 690
           
 Score =  104 bits (257), Expect = 1e-22
 Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 31/162 (19%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + I+G DI+  +I  LR++IGVV Q+  LF  TI EN+++GR+D T EE+    +++   
Sbjct: 493 ILINGRDIKEYDIDALRKVIGVVPQDTPLFNDTIWENVKFGRIDATDEEVITVVEKAQLA 552

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
             I  LP                            Q F+T+VG+RG  +SGG+KQR+AIA
Sbjct: 553 PLIKKLP----------------------------QGFDTIVGERGLMISGGEKQRLAIA 584

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCSPS 162
           R L++N +I+  DEATSALD  +E   QA L  ++    S S
Sbjct: 585 RVLLKNARIMFFDEATSALDTHTE---QALLRTIRDNFTSGS 623


>sp|P11599|HLYB_PROVU HEMOLYSIN SECRETION ATP-BINDING PROTEIN.
           Length = 707
           
 Score =  104 bits (256), Expect = 2e-22
 Identities = 61/154 (39%), Positives = 84/154 (53%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  +GVV Q+ VL   +I +NI      +  E++  A K + A+
Sbjct: 526 VLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNIALADPGMPVEKVIHAAKLAGAH 585

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  L                             + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 586 DFISEL----------------------------REGYNTIVGEQGAGLSGGQRQRIAIA 617

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NPKIL+ DEATSALD ESE ++   + K+
Sbjct: 618 RALVNNPKILIFDEATSALDYESEHVIMRNMHKI 651


>sp|P75094|Y015_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG015 HOMOLOG.
           Length = 634
           
 Score =  103 bits (255), Expect = 2e-22
 Identities = 58/160 (36%), Positives = 87/160 (54%), Gaps = 28/160 (17%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           +++D  +I  ++    RE I +V Q+P LF+ TI ENIR GR D T EEI  A K +NA+
Sbjct: 454 IYMDNFEISEVSETAWREKISIVLQDPFLFSGTIKENIRMGRQDATDEEIIEACKVANAH 513

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                            Q + T + ++   LS G++Q + IA
Sbjct: 514 DFIMRLP----------------------------QGYNTFISNKTDYLSVGERQLLTIA 545

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           RA++RN  +LLLDEATS++D  SE ++Q ++ ++     S
Sbjct: 546 RAVIRNAPVLLLDEATSSIDVHSEKLIQQSIGRLMKDKTS 585


>sp|P54719|YFIC_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 2 IN GLVBC
           3'REGION.
           Length = 604
           
 Score =  102 bits (253), Expect = 3e-22
 Identities = 59/154 (38%), Positives = 88/154 (56%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DI++L    LR+ +G V Q+  LF  TI ENIRYGRLD + +E+E A K +NA+
Sbjct: 423 ILIDGTDIKTLTRASLRKNMGFVLQDSFLFQGTIRENIRYGRLDASDQEVEAAAKTANAH 482

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            FI  LP                            + ++T++   G+ +S GQKQ I+IA
Sbjct: 483 SFIERLP----------------------------KGYDTVLTQNGSGISQGQKQLISIA 514

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RA++ +P +L+LDEATS +D  +E  +Q AL ++
Sbjct: 515 RAVLADPVLLILDEATSNIDTVTEVNIQEALARL 548


>sp|P18770|CYAB_BORPE CYCLOLYSIN SECRETION ATP-BINDING PROTEIN CYAB.
           Length = 712
           
 Score =  102 bits (253), Expect = 3e-22
 Identities = 58/148 (39%), Positives = 82/148 (55%), Gaps = 28/148 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHDI  ++   LR  +GVV QE  LF  ++ +NI   R   +  E+  A + + A+
Sbjct: 529 VLIDGHDIGIVDSASLRRQLGVVLQESTLFNRSVRDNIALTRPGASMHEVVAAARLAGAH 588

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           +FI  LP+                             ++T++G+ G  LSGGQ+QRI IA
Sbjct: 589 EFICQLPE----------------------------GYDTMLGENGVGLSGGQRQRIGIA 620

Query: 121 RALVRNPKILLLDEATSALDAESETIVQ 148
           RAL+  P++L+LDEATSALD ESE I+Q
Sbjct: 621 RALIHRPRVLILDEATSALDYESEHIIQ 648


>sp|P26760|RT1B_ACTPL RTX-I TOXIN DETERMINANT B (TOXIN RTX-I SECRETION ATP-BINDING
           PROTEIN) (APX-IB) (HLY-IB) (CYTOLYSIN IB) (CLY-IB).
           Length = 707
           
 Score =  102 bits (253), Expect = 3e-22
 Identities = 61/154 (39%), Positives = 84/154 (53%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  +GVV Q+ VL   +I +NI      +  E+I  A K + A+
Sbjct: 526 VLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIRDNIALADPGMPMEKIVHAAKLAGAH 585

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           +FI  L                             + + T+VG++G  LSGGQ+QRIAIA
Sbjct: 586 EFISEL----------------------------REGYNTIVGEQGAGLSGGQRQRIAIA 617

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NPKIL+ DEATSALD ESE I+   + ++
Sbjct: 618 RALVNNPKILIFDEATSALDYESEHIIMRNMHQI 651


>sp|Q04473|RT3B_ACTPL RTX-III TOXIN DETERMINANT B (TOXIN RTX-III SECRETION ATP-BINDING
           PROTEIN) (APX-IIIB) (CYTOLYSIN IIIB) (CLY-IIIB).
           Length = 711
           
 Score =  102 bits (253), Expect = 3e-22
 Identities = 62/154 (40%), Positives = 83/154 (53%), Gaps = 28/154 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDGHD+   +  +LR  IGVV Q+ VL   +I +NI      ++ E +  A K + A+
Sbjct: 530 VLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRDNIALTDPSMSMERVIYAAKLAGAH 589

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  L                             + + T+VG+ G  LSGGQ+QRIAIA
Sbjct: 590 DFISEL----------------------------REGYNTIVGELGAGLSGGQRQRIAIA 621

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           RALV NP+IL+ DEATSALD ESE I+   + K+
Sbjct: 622 RALVNNPRILIFDEATSALDYESEHIIMQNMQKI 655


>sp|P33310|MDL1_YEAST ATP-DEPENDENT PERMEASE MDL1.
           Length = 695
           
 Score =  102 bits (252), Expect = 4e-22
 Identities = 62/150 (41%), Positives = 82/150 (54%), Gaps = 31/150 (20%)

Query: 7   DIRSLNIRYLREMIGVVSQEPVLFATTITENIRY---GRLDVTQEEIERATKESNAYDFI 63
           DIR+ N+R  R +IG V QEP+LF  TI +NI Y     +    + I RA  ++N   F+
Sbjct: 497 DIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFL 556

Query: 64  MNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARAL 123
            N PD                              +T+VG RG QLSGGQKQRIA+ARA 
Sbjct: 557 ANFPD----------------------------GLQTMVGARGAQLSGGQKQRIALARAF 588

Query: 124 VRNPKILLLDEATSALDAESETIVQAALDK 153
           + +P +L+LDEATSALD++SE IV   L +
Sbjct: 589 LLDPAVLILDEATSALDSQSEEIVAKNLQR 618


>sp|P36370|TAP1_RAT ANTIGEN PEPTIDE TRANSPORTER 1 (APT1).
           Length = 725
           
 Score =  100 bits (246), Expect = 2e-21
 Identities = 59/152 (38%), Positives = 79/152 (51%), Gaps = 29/152 (19%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDV-TQEEIERATKESNA 59
           V +DG  +   +  YL   +  V QEP+LF  +  ENI YG     T EEI     ES A
Sbjct: 539 VLLDGEPLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLTRTPTMEEITAVAMESGA 598

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
           +DFI   P                            Q ++T VG+ G QLSGGQ+Q +A+
Sbjct: 599 HDFISGFP----------------------------QGYDTEVGETGNQLSGGQRQAVAL 630

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAAL 151
           ARAL+R P++L+LD+ATSALDA ++  VQ  L
Sbjct: 631 ARALIRKPRLLILDDATSALDAGNQLRVQRLL 662


>sp|P47261|Y015_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG015.
           Length = 589
           
 Score = 99.5 bits (244), Expect = 4e-21
 Identities = 55/160 (34%), Positives = 87/160 (54%), Gaps = 28/160 (17%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           +++D  +I  +  +  RE I +V Q+  LF+ TI ENIR GR D T +EI  A K +NA+
Sbjct: 409 IYMDNFEISDVTKKAWREKISIVLQDSFLFSGTIKENIRLGRQDATDDEIIAACKTANAH 468

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFIM LP                            + ++T + ++   LS G++Q + IA
Sbjct: 469 DFIMRLP----------------------------KGYDTYISNKADYLSVGERQLLTIA 500

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           RA++RN  +LLLDEATS++D  SE ++Q ++ ++     S
Sbjct: 501 RAVIRNAPVLLLDEATSSVDVHSEKLIQESIGRLMKNKTS 540


>sp|P18767|NDVA_RHIME BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTEIN NDVA.
           Length = 616
           
 Score = 97.9 bits (240), Expect = 1e-20
 Identities = 60/155 (38%), Positives = 89/155 (56%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DI ++  + LR  I  V Q+  L   +I ENIR GR D + +E+  A + + A 
Sbjct: 423 ILIDGVDIATVTRKSLRRSIATVFQDAGLMNRSIGENIRLGREDASLDEVMAAAEAAAAS 482

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI +                  R N           ++T+VG+RG +LSGG++QR+AIA
Sbjct: 483 DFIED------------------RLNG----------YDTVVGERGNRLSGGERQRVAIA 514

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RA+++N  IL+LDEATSALD E+E  V+ A+D ++
Sbjct: 515 RAILKNAPILVLDEATSALDVETEARVKDAIDALR 549


>sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 1 IN GLVBC
           3'REGION.
           Length = 573
           
 Score = 97.9 bits (240), Expect = 1e-20
 Identities = 58/160 (36%), Positives = 88/160 (54%), Gaps = 31/160 (19%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           ++ID   ++ +    LR  IG V QE +LF+ TI ENI +G+ + + +EI  A K +  +
Sbjct: 388 IYIDEKPVQDIPAEGLRRQIGYVPQEVLLFSGTIKENIAWGKENASLDEIMDAAKLAQIH 447

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           + I+ LP+                             ++T++G RG  LSGGQKQRI+IA
Sbjct: 448 ETILKLPN----------------------------GYDTVLGQRGVNLSGGQKQRISIA 479

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           RAL+R P ILLLD++TSALD ++E      L+ + T  C+
Sbjct: 480 RALIRKPAILLLDDSTSALDLQTEA---KLLEAISTYHCT 516


>sp|P21958|TAP1_MOUSE ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (HISTOCOMPATIBILITY ANTIGEN
           MODIFIER 1).
           Length = 724
           
 Score = 97.5 bits (239), Expect = 2e-20
 Identities = 63/185 (34%), Positives = 90/185 (48%), Gaps = 29/185 (15%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYG-RLDVTQEEIERATKESNA 59
           + +DG  +   +  YL   +  V QEP+LF  +  ENI YG     T EEI     ES A
Sbjct: 538 LLLDGQRLVQYDHHYLHTQVAAVGQEPLLFGRSFRENIAYGLNRTPTMEEITAVAVESGA 597

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
           +DFI   P                            Q ++T VG+ G QLSGGQ+Q +A+
Sbjct: 598 HDFISGFP----------------------------QGYDTEVGETGNQLSGGQRQAVAL 629

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCSPSPCRTQPLDLKDISQYGQ 179
           ARAL+R P +L+LD+ATSALDA ++  VQ  L +   +        TQ L L + + +  
Sbjct: 630 ARALIRKPLLLILDDATSALDAGNQLRVQRLLYESPKRASRTVLLITQQLSLAEQAHHIL 689

Query: 180 YVFSG 184
           ++  G
Sbjct: 690 FLREG 694


>sp|P18768|CHVA_AGRTU BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTEIN CHVA (ATTACHMENT
           PROTEIN).
           Length = 588
           
 Score = 96.7 bits (237), Expect = 3e-20
 Identities = 63/155 (40%), Positives = 84/155 (53%), Gaps = 28/155 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DI ++    LR  I  V Q+  L   +I ENIR GR   T  E+  A   + A 
Sbjct: 392 ILIDGTDISTVTKNSLRNSIATVFQDAGLLNRSIRENIRLGRETATDAEVVEAAAAAAAT 451

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI                     S  N Y+        T VG+RG +LSGG++QRIAIA
Sbjct: 452 DFI--------------------DSRINGYL--------TQVGERGNRLSGGERQRIAIA 483

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           RA+++N  IL+LDEATSALD E+E  V+AA+D ++
Sbjct: 484 RAILKNAPILVLDEATSALDVETEARVKAAVDALR 518


>sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANSPORTER 2 (APT2).
           Length = 703
           
 Score = 96.0 bits (235), Expect = 4e-20
 Identities = 55/148 (37%), Positives = 81/148 (54%), Gaps = 28/148 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + +DG  +   +  YL   + +V QEPVLF+ ++ +NI YG  D    ++  A + + A 
Sbjct: 527 LLLDGEPLVQYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACAD 586

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  + +                               T +G++G+QL+ GQKQR+AIA
Sbjct: 587 DFIGEMTN----------------------------GINTEIGEKGSQLAVGQKQRLAIA 618

Query: 121 RALVRNPKILLLDEATSALDAESETIVQ 148
           RALVRNP++L+LDEATSALDAE E  +Q
Sbjct: 619 RALVRNPRVLILDEATSALDAECEQALQ 646


>sp|Q03518|TAP1_HUMAN ANTIGEN PEPTIDE TRANSPORTER 1 (APT1) (PEPTIDE TRANSPORTER TAP1)
           (PEPTIDE TRANSPORTER PSF1) (PEPTIDE SUPPLY FACTOR 1)
           (PSF-1) (PEPTIDE TRANSPORTER INVOLVED IN ANTIGEN
           PROCESSING 1).
           Length = 748
           
 Score = 95.2 bits (233), Expect = 8e-20
 Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 29/152 (19%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDV-TQEEIERATKESNA 59
           + +DG  +     RYL   +  V QEP +F  ++ ENI YG     T EEI  A  +S A
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
           + FI  LP                            Q ++T V + G+QLSGGQ+Q +A+
Sbjct: 622 HSFISGLP----------------------------QGYDTEVDEAGSQLSGGQRQAVAL 653

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAAL 151
           ARAL+R P +L+LD+ATSALDA S+  V+  L
Sbjct: 654 ARALIRKPCVLILDDATSALDANSQLQVEQLL 685


>sp|P22520|CVAB_ECOLI COLICIN V SECRETION ATP-BINDING PROTEIN CVAB.
           Length = 698
           
 Score = 94.4 bits (231), Expect = 1e-19
 Identities = 60/151 (39%), Positives = 79/151 (51%), Gaps = 28/151 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V I+G DIR + I     MI  V Q+  LF+ +I ENI     ++ +E +    + S+ +
Sbjct: 550 VLINGIDIRQIGINNYHRMIACVMQDDRLFSGSIRENICGFAEEMDEEWMVECARASHIH 609

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           D IMN+P                              +ETL+G+ G  LSGGQKQRI IA
Sbjct: 610 DVIMNMP----------------------------MGYETLIGELGEGLSGGQKQRIFIA 641

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAAL 151
           RAL R P IL +DEATSALD+ESE  V  A+
Sbjct: 642 RALYRKPGILFMDEATSALDSESEHFVNVAI 672


>sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (HISTOCOMPATIBILITY ANTIGEN
           MODIFIER 2).
           Length = 702
           
 Score = 94.4 bits (231), Expect = 1e-19
 Identities = 54/148 (36%), Positives = 80/148 (53%), Gaps = 28/148 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + +DG  +   +  YL   + +V QEPVLF+ ++ +NI YG  D    ++  A + + A 
Sbjct: 526 LLLDGEPLTEYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACAD 585

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  + +                               T +G++G QL+ GQKQR+AIA
Sbjct: 586 DFIGEMTN----------------------------GINTEIGEKGGQLAVGQKQRLAIA 617

Query: 121 RALVRNPKILLLDEATSALDAESETIVQ 148
           RALVRNP++L+LDEATSALDA+ E  +Q
Sbjct: 618 RALVRNPRVLILDEATSALDAQCEQALQ 645


>sp|P54683|TAGB_DICDI PRESTALK-SPECIFIC PROTEIN TAGB PRECURSOR (EC 3.4.21.-).
            Length = 1905
            
 Score = 90.9 bits (222), Expect = 1e-18
 Identities = 60/157 (38%), Positives = 84/157 (53%), Gaps = 30/157 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            +++DG DI  +    LR  +  V Q P LF  TI ENI Y   + TQE+I  A K + A+
Sbjct: 1580 IYMDGIDIAKIRPNNLRSFVTNVHQHPFLFDATIGENIGYAIDNPTQEDIIEAAKLAYAH 1639

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            +FI +LP                            +K++T +G+ G  LSGGQK+RIA+A
Sbjct: 1640 EFINDLP----------------------------KKYDTQIGEAGN-LSGGQKKRIAVA 1670

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
            RA+    KI+LLDE T+ LD ESE  +  ++ KV TQ
Sbjct: 1671 RAICAKRKIMLLDEITAELDPESEEAITQSI-KVLTQ 1706


>sp|Q03519|TAP2_HUMAN ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (PEPTIDE TRANSPORTER TAP2)
           (PEPTIDE TRANSPORTER PSF2) (PEPTIDE SUPPLY FACTOR 2)
           (PSF-2) (PEPTIDE TRANSPORTER INVOLVED IN ANTIGEN
           PROCESSING 2).
           Length = 686
           
 Score = 90.5 bits (221), Expect = 2e-18
 Identities = 54/148 (36%), Positives = 77/148 (51%), Gaps = 28/148 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V +D   I      YL   +  V QEPVLF+ ++  NI YG      +++  A + ++A 
Sbjct: 527 VLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHAD 586

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           DFI  +                            E    T VG++G+QL+ GQKQR+AIA
Sbjct: 587 DFIQEM----------------------------EHGIYTDVGEKGSQLAAGQKQRLAIA 618

Query: 121 RALVRNPKILLLDEATSALDAESETIVQ 148
           RALVR+P++L+LDEATSALD + E  +Q
Sbjct: 619 RALVRDPRVLILDEATSALDVQCEQALQ 646


>sp|Q57538|Y664_HAEIN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN HI0664.
           Length = 552
           
 Score = 88.2 bits (215), Expect = 1e-17
 Identities = 53/155 (34%), Positives = 83/155 (53%), Gaps = 28/155 (18%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           I+G  + ++N   LR+ +  ++Q+  +F  TI ENIR  R D T EEI  A K+++ +DF
Sbjct: 398 INGETLPNINTCSLRDNMAYITQQTYIFNETIEENIRLARRDATLEEIMEAAKKASIHDF 457

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
           I++LP                            Q ++T + + G  LS G+KQRI IARA
Sbjct: 458 ILSLP----------------------------QGYQTKMTELGGNLSDGEKQRIGIARA 489

Query: 123 LVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
            + N  I+LLDE TS LD+ +E ++  +L  V+ +
Sbjct: 490 FLHNAPIILLDEPTSNLDSLNEAMILKSLLNVKAE 524


>sp|P30751|MDL_ECOLI MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDL.
           Length = 1143
           
 Score = 88.2 bits (215), Expect = 1e-17
 Identities = 55/141 (39%), Positives = 76/141 (53%), Gaps = 30/141 (21%)

Query: 6   HDI--RSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDFI 63
           HDI    L +   R  + VVSQ P LF+ T+  NI  G  + TQ+EIE   + ++ +D I
Sbjct: 367 HDIPLTKLQLDSWRTGLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLASVHDDI 426

Query: 64  MNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARAL 123
           + LP                            Q ++T VG+RG  LSGGQKQRI+IARAL
Sbjct: 427 LRLP----------------------------QGYDTEVGERGVMLSGGQKQRISIARAL 458

Query: 124 VRNPKILLLDEATSALDAESE 144
           + N +IL+LD+A SA+D  +E
Sbjct: 459 LVNAEILILDDALSAVDGRTE 479


 Score = 71.8 bits (173), Expect = 8e-13
 Identities = 49/156 (31%), Positives = 80/156 (50%), Gaps = 30/156 (19%)

Query: 3    IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
            +DG  + SL+     + + +V Q+PV+ A T   N+  GR D+++E + +A +     D 
Sbjct: 959  LDGRPLSSLS-HTRGQGVAMVQQDPVVLADTFLANVTLGR-DISEERVWQALETVQLADV 1016

Query: 63   IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
              ++ D                    IY         T +G++G  LS GQKQ +A+AR 
Sbjct: 1017 ARSMSD-------------------GIY---------TPLGEQGNNLSVGQKQLLALARV 1048

Query: 123  LVRNPKILLLDEATSALDAESETIVQAALDKVQTQT 158
            LV  P+IL+LDEAT+++D+ +E  +Q AL  V+  T
Sbjct: 1049 LVETPQILILDEATASIDSGTEQAIQHALAAVREHT 1084


>sp|Q23868|TAGC_DICDI PRESTALK-SPECIFIC PROTEIN TAGC PRECURSOR (EC 3.4.21.-).
            Length = 1743
            
 Score = 87.8 bits (214), Expect = 1e-17
 Identities = 57/157 (36%), Positives = 83/157 (52%), Gaps = 29/157 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + +D  DI ++    LR  +  V Q P LF  +I +NI Y   + T EE+  A K + A+
Sbjct: 1510 IIMDDIDIANIRPNNLRGFVTCVHQNPYLFDASIKDNIGYALDNPTIEEVIEAAKLAYAH 1569

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            +FI +LP                            Q+++T++G  G+ LSGGQK+RIAIA
Sbjct: 1570 EFIKDLP----------------------------QQYDTVLGSAGSLLSGGQKKRIAIA 1601

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
            RA+    KI+LLDE T+ LD ESE  +  ++ KV TQ
Sbjct: 1602 RAICAKRKIMLLDEITAELDPESEEAITQSI-KVLTQ 1637


>sp|Q11047|Y08A_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN CY50.10.
           Length = 631
           
 Score = 87.0 bits (212), Expect = 2e-17
 Identities = 53/160 (33%), Positives = 83/160 (51%), Gaps = 28/160 (17%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + IDG DI S++ + LR  IG+V Q+  L+  TI ENI YGR + T +EI  A + ++  
Sbjct: 454 ILIDGVDIASVSRQSLRSRIGMVLQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVD 513

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            F+  LP                              ++T V   G  +S G+KQ I IA
Sbjct: 514 RFVNTLP----------------------------AGYQTRVSGDGGSISVGEKQLITIA 545

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           RA +  P++L+LDEATS++D  +E ++Q A+ +++    S
Sbjct: 546 RAFLARPQLLILDEATSSVDTRTELLIQRAMRELRRDRTS 585


>sp|Q11019|Y07D_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN CY02B10.13.
           Length = 579
           
 Score = 84.3 bits (205), Expect = 1e-16
 Identities = 54/151 (35%), Positives = 80/151 (52%), Gaps = 28/151 (18%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           V IDG D+ +L+ R  + +  VV Q P LF  TI +N+       + ++  +A + +   
Sbjct: 390 VLIDGTDVATLDARAQQAVCSVVFQHPYLFHGTIRDNVFAADPGASDDQFAQAVRLARVD 449

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           + I  LPD                  AN           T+VG+ G+ LSGG++QR++IA
Sbjct: 450 ELIARLPD-----------------GAN-----------TIVGEAGSALSGGERQRVSIA 481

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAAL 151
           RAL++   +LL+DEATSALDAE+E  V  AL
Sbjct: 482 RALLKAAPVLLVDEATSALDAENEAAVVDAL 512


>sp|P12866|STE6_YEAST MATING FACTOR A SECRETION PROTEIN STE6 (MULTIPLE DRUG RESISTANCE
            PROTEIN HOMOLOG) (P-GLYCOPROTEIN).
            Length = 1290
            
 Score = 84.3 bits (205), Expect = 1e-16
 Identities = 56/152 (36%), Positives = 79/152 (51%), Gaps = 31/152 (20%)

Query: 3    IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD-VTQEEIERATKESNAYD 61
            IDG D+   N+  LR+ I VV Q+P+LF  TI +N+ YG  D + + E+  A K    +D
Sbjct: 1113 IDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTYGLQDEILEIEMYDALKYVGIHD 1172

Query: 62   FIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIAR 121
            F+++ P                            Q  +T +    T LSGGQ QR+ IAR
Sbjct: 1173 FVISSP----------------------------QGLDTRIDT--TLLSGGQAQRLCIAR 1202

Query: 122  ALVRNPKILLLDEATSALDAESETIVQAALDK 153
            AL+R  KIL+LDE TSALD+ S +I+   + K
Sbjct: 1203 ALLRKSKILILDECTSALDSVSSSIINEIVKK 1234


 Score = 74.5 bits (180), Expect = 1e-13
 Identities = 52/151 (34%), Positives = 79/151 (51%), Gaps = 18/151 (11%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + I+GH+I++++ + L E I VV Q   LF  T+ +NI  G  D  +   + +T E+   
Sbjct: 416 ISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILLGSTDSVRNA-DCSTNENR-- 472

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
                      HL    +  A   +  + +I+      ETL+G  G  LSGGQ+QR+AIA
Sbjct: 473 -----------HL----IKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIA 517

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAAL 151
           RA +R+  IL LDEA SALD     ++  A+
Sbjct: 518 RAFIRDTPILFLDEAVSALDIVHRNLLMKAI 548


>sp|P16877|MDR4_ENTHI MULTIDRUG RESISTANCE PROTEIN 4 (P-GLYCOPROTEIN) (FRAGMENT).
           Length = 113
           
 Score = 80.0 bits (194), Expect = 3e-15
 Identities = 48/120 (40%), Positives = 66/120 (55%), Gaps = 32/120 (26%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYG---RLDVTQEEIERATKES 57
           V +DGH+IR     +LR  IG+V QEPVLFA ++ +NIR G    ++V+ E+I  A K +
Sbjct: 23  VLLDGHNIR-FEYSFLRSQIGMVGQEPVLFAESVMDNIRRGVPKGVEVSNEQIYAAAKMA 81

Query: 58  NAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
           NA+DFI  +P+                             + T+VGDRG Q+SGGQKQRI
Sbjct: 82  NAHDFISAMPE----------------------------GYNTMVGDRGAQISGGQKQRI 113


>sp|P47260|Y014_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG014.
           Length = 623
           
 Score = 79.6 bits (193), Expect = 4e-15
 Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 18/152 (11%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + I G  I+S++  YL EMIG+V Q+ +LF  TI+ NI+ G        IE  +   N  
Sbjct: 424 ILIGGEKIQSIDSLYLSEMIGIVFQQNILFKGTISSNIKIG--------IETRSDWKNQS 475

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
           D   N            +  A   + A+ +I      ++  V   G  LSGGQKQR+AIA
Sbjct: 476 DLQKN----------EAMKNAAKIACADTFIEKFSDSYDHNVEQLGKNLSGGQKQRVAIA 525

Query: 121 RALVRNPKILLLDEATSALDAESETIVQAALD 152
           R L+  P+IL+ D++ SALDA +E  V+  ++
Sbjct: 526 RTLITKPRILVFDDSMSALDALTEKKVRENIE 557


>sp|Q11018|Y07C_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN CY02B10.12.
           Length = 859
           
 Score = 77.6 bits (188), Expect = 1e-14
 Identities = 50/152 (32%), Positives = 78/152 (50%), Gaps = 29/152 (19%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           + G DIRSL    L   +G V QE  L   T  ENI     D   E+++ A +E+  +D 
Sbjct: 669 VGGQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAAREAQIHDR 728

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
           ++ LPD                             ++T++G   + LSGG++QR+ IARA
Sbjct: 729 VLRLPD----------------------------GYDTVLG-ANSGLSGGERQRLTIARA 759

Query: 123 LVRNPKILLLDEATSALDAESETIVQAALDKV 154
           ++ +  +L+LDEAT+  D ESE +VQ AL+++
Sbjct: 760 ILGDTPVLILDEATAFADPESEYLVQQALNRL 791


>sp|P16876|MDR3_ENTHI MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN) (FRAGMENT).
           Length = 114
           
 Score = 77.6 bits (188), Expect = 1e-14
 Identities = 47/119 (39%), Positives = 64/119 (53%), Gaps = 29/119 (24%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENI--RYGRLDVTQEEIERATKESN 58
           V +DG+D+R LN+++LR  IG+V QEP+LFA TI ENI         T+EE+    K +N
Sbjct: 23  VTLDGNDLRELNLKWLRNQIGLVGQEPILFACTIRENIMLELKWRTPTEEEMLECAKMAN 82

Query: 59  AYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
           A++FI                             I +Q ++T+VG RG  LSGGQKQRI
Sbjct: 83  AHEFI---------------------------FFIFQQGYDTMVGARGAALSGGQKQRI 114


>sp|P75095|Y014_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG014 HOMOLOG.
           Length = 623
           
 Score = 77.6 bits (188), Expect = 1e-14
 Identities = 49/148 (33%), Positives = 79/148 (53%), Gaps = 18/148 (12%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           +F+ G  I++++  YL +MIG+V Q+ +LF  TI  NI+ G       + E  +K+  A 
Sbjct: 424 IFVGGQSIKTIDSDYLAKMIGIVFQQNILFKGTIASNIKIGLETREDWKHEPDSKKDAA- 482

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
                            +  A + + A+ +I      ++  V   G  LSGGQKQR+AIA
Sbjct: 483 -----------------MKRAAAIACADTFIEKFSDTYDHTVEQLGKNLSGGQKQRVAIA 525

Query: 121 RALVRNPKILLLDEATSALDAESETIVQ 148
           R ++  P+IL+LD++ SALDA +E  V+
Sbjct: 526 RTVITKPQILVLDDSMSALDALTEKKVR 553


>sp|P16875|MDR1_ENTHI MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN) (FRAGMENT).
           Length = 114
           
 Score = 77.3 bits (187), Expect = 2e-14
 Identities = 45/120 (37%), Positives = 66/120 (54%), Gaps = 31/120 (25%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD---VTQEEIERATKES 57
           V +DG DIR LNI++LR  IG+V QEPVLFA TI ENI  G  +   ++++E+    K +
Sbjct: 23  VTLDGKDIRELNIKWLRNQIGLVGQEPVLFAGTIRENIMLGAKEGETLSKDEMIECAKMA 82

Query: 58  NAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
           NA++F+  L                             + ++TL+G++G  LSGGQ+QRI
Sbjct: 83  NAHEFVSKL----------------------------AEGYDTLIGEKGALLSGGQRQRI 114


>sp|Q11046|Y089_MYCTU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN CY50.09.
           Length = 582
           
 Score = 76.1 bits (184), Expect = 4e-14
 Identities = 50/157 (31%), Positives = 75/157 (46%), Gaps = 33/157 (21%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLD---VTQEEIERATKES 57
           V +DG D+R  +   L   IG+V Q   LF+ T+ +N+RYG      VT++E+  A + +
Sbjct: 393 VLVDGIDVREYHTERLWSAIGLVPQRSYLFSGTVADNLRYGGGPDQVVTEQEMWEALRVA 452

Query: 58  NAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
            A  F+                                   +T V   G   SGGQ+QR+
Sbjct: 453 AADGFVQT------------------------------DGLQTRVAQGGVNFSGGQRQRL 482

Query: 118 AIARALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           AIARA++R P I + D+A SALD  ++  V A+L +V
Sbjct: 483 AIARAVIRRPAIYVFDDAFSALDVHTDAKVHASLRQV 519


>sp|P45082|CYDD_HAEIN TRANSPORT ATP-BINDING PROTEIN CYDD.
           Length = 586
           
 Score = 75.7 bits (183), Expect = 6e-14
 Identities = 61/186 (32%), Positives = 85/186 (44%), Gaps = 34/186 (18%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           I+G ++R  N+   R+ I  V Q P+L   TI EN+  G +    EEI +A   S A +F
Sbjct: 408 INGQELRESNLADWRKHIAWVGQNPLLLQGTIKENLLLGDVQANDEEINQALMRSQAKEF 467

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
              L                                   + D G  +S GQ QR+AIARA
Sbjct: 468 TDKLG------------------------------LHHEIKDGGLGISVGQAQRLAIARA 497

Query: 123 LVRNPKILLLDEATSALDAESETIVQAALDKV-QTQTCSPSPCRTQPLDLKD---ISQYG 178
           L+R   +LLLDE T++LDA+SE +V  AL++  Q QT      R + L   D   + Q G
Sbjct: 498 LLRKGDLLLLDEPTASLDAQSENLVLQALNEASQHQTTLMITHRIEDLKQCDQIFVMQRG 557

Query: 179 QYVFSG 184
           + V  G
Sbjct: 558 EIVQQG 563


>sp|Q03024|APRD_PSEAE ALKALINE PROTEASE SECRETION ATP-BINDING PROTEIN APRD.
           Length = 593
           
 Score = 74.9 bits (181), Expect = 1e-13
 Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 31/161 (19%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENI-RYGRLDVTQEEIERATKESNA 59
           V +DG +IR      L   IG + Q+  LFA T+ ENI R+G  +V  +++  A + +  
Sbjct: 390 VRLDGAEIRQYERETLGPRIGYLPQDIELFAGTVAENIARFG--EVQADKVVEAARLAGV 447

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
           ++ ++ LP                            Q ++T++G  G  LSGGQ+QRIA+
Sbjct: 448 HELVLRLP----------------------------QGYDTVLGVGGAGLSGGQRQRIAL 479

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           ARAL   P +++LDE  S LD   E  + AA+  ++ + C+
Sbjct: 480 ARALYGAPTLVVLDEPNSNLDDSGEQALLAAIQALKARGCT 520


>sp|P38735|YHD5_YEAST PROBABLE ATP-DEPENDENT PERMEASE YHL035C.
            Length = 1592
            
 Score = 73.7 bits (178), Expect = 2e-13
 Identities = 49/150 (32%), Positives = 84/150 (55%), Gaps = 16/150 (10%)

Query: 3    IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIR-YGRLDVTQEEIERATKESNAYD 61
            IDG DI  +++  LR  I ++ Q+P+LFA TI  N+  Y   D  +++I +A  + N   
Sbjct: 1383 IDGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNVDPYDEYD--EKKIFKALSQVNL-- 1438

Query: 62   FIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIAR 121
                   +  H +   L+ +  R N+     ++     T + + G  LS G++Q + IAR
Sbjct: 1439 -------ISSHEFEEVLN-SEERFNSTHNKFLN---LHTEIAEGGLNLSQGERQLLFIAR 1487

Query: 122  ALVRNPKILLLDEATSALDAESETIVQAAL 151
            +L+R PKI+LLDEATS++D +S+ ++Q  +
Sbjct: 1488 SLLREPKIILLDEATSSIDYDSDHLIQGII 1517


 Score = 48.4 bits (113), Expect = 9e-06
 Identities = 22/44 (50%), Positives = 34/44 (77%)

Query: 100 TLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAES 143
           T +G++G  LSGGQKQRI++ARA+  + K +LLD+  SA+D+ +
Sbjct: 799 TEIGEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHT 842


>sp|P94367|CYDD_BACSU TRANSPORT ATP-BINDING PROTEIN CYDD.
           Length = 575
           
 Score = 72.6 bits (175), Expect = 5e-13
 Identities = 41/129 (31%), Positives = 68/129 (51%), Gaps = 28/129 (21%)

Query: 16  LREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWL 75
           + + + V++Q+P LF T+I  NIR G  + + E++ RA K+   +D+I +LPD       
Sbjct: 408 IADAVAVLNQKPHLFDTSILNNIRLGNGEASDEDVRRAAKQVKLHDYIESLPD------- 460

Query: 76  PYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEA 135
                                 + T V + G + SGG++QRIA+AR L+++  I++LDE 
Sbjct: 461 ---------------------GYHTSVQETGIRFSGGERQRIALARILLQDTPIIILDEP 499

Query: 136 TSALDAESE 144
           T  LD  +E
Sbjct: 500 TVGLDPITE 508


>sp|P29018|CYDD_ECOLI TRANSPORT ATP-BINDING PROTEIN CYDD.
           Length = 588
           
 Score = 72.2 bits (174), Expect = 6e-13
 Identities = 48/150 (32%), Positives = 75/150 (50%), Gaps = 28/150 (18%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           I+G ++R L+    R+ +  V Q P L A T+ +N+   R D +++E++ A   +   +F
Sbjct: 408 INGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEF 467

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
           +  LP                            Q  +T VGD+  +LS GQ QR+A+ARA
Sbjct: 468 LPLLP----------------------------QGVDTPVGDQAARLSVGQAQRVAVARA 499

Query: 123 LVRNPKILLLDEATSALDAESETIVQAALD 152
           L+    +LLLDE  ++LDA SE  V  AL+
Sbjct: 500 LLNPCSLLLLDEPAASLDAHSEQRVMEALN 529


>sp|P33527|MRP1_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1.
            Length = 1531
            
 Score = 70.6 bits (170), Expect = 2e-12
 Identities = 46/160 (28%), Positives = 82/160 (50%), Gaps = 30/160 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + IDG +I  + +  LR  I ++ Q+PVLF+ ++  N+       + EE+  + + ++  
Sbjct: 1351 IIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFS-QYSDEEVWTSLELAHLK 1409

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            DF+  LPD                            K +    + G  LS GQ+Q + +A
Sbjct: 1410 DFVSALPD----------------------------KLDHECAEGGENLSVGQRQLVCLA 1441

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
            RAL+R  KIL+LDEAT+A+D E++ ++Q+ + + Q + C+
Sbjct: 1442 RALLRKTKILVLDEATAAVDLETDDLIQSTI-RTQFEDCT 1480


 Score = 49.2 bits (115), Expect = 5e-06
 Identities = 22/42 (52%), Positives = 31/42 (73%)

Query: 100 TLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 141
           T +G++G  LSGGQKQR+++ARA+  N  I L D+  SA+DA
Sbjct: 759 TEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDA 800


>sp|P23596|PRTD_ERWCH PROTEASES SECRETION ATP-BINDING PROTEIN PRTD.
           Length = 575
           
 Score = 69.5 bits (167), Expect = 4e-12
 Identities = 46/156 (29%), Positives = 79/156 (50%), Gaps = 31/156 (19%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENI-RYGRLDVTQEEIERATKESNA 59
           V +DG D+  ++       IG + Q+  LF  ++ ENI R+G  D   E++  A K +  
Sbjct: 388 VRLDGADLNQVDKNTFGPTIGYLPQDVQLFKGSLAENIARFG--DADPEKVVAAAKLAGV 445

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
           ++ I++LP+                             ++T +GD G  LSGGQ+QRI +
Sbjct: 446 HELILSLPN----------------------------GYDTELGDGGGGLSGGQRQRIGL 477

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           ARA+  +P +L+LDE  ++LD+E +  +  A+  +Q
Sbjct: 478 ARAMYGDPCLLILDEPNASLDSEGDQALMQAIVALQ 513


>sp|Q92887|MRP2_HUMAN CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER (MULTIDRUG
            RESISTANCE-ASSOCIATED PROTEIN 2) (CANALICULAR MULTIDRUG
            RESISTANCE PROTEIN).
            Length = 1545
            
 Score = 69.1 bits (166), Expect = 5e-12
 Identities = 44/151 (29%), Positives = 81/151 (53%), Gaps = 29/151 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + IDG DI S+ +  LRE + ++ Q+P+LF+ ++  N+     + + EEI +A + ++  
Sbjct: 1358 IIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFN-NYSDEEIWKALELAHLK 1416

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
             F+                       A++ + +S +     V + G  LS GQ+Q + + 
Sbjct: 1417 SFV-----------------------ASLQLGLSHE-----VTEAGGNLSIGQRQLLCLG 1448

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAAL 151
            RAL+R  KIL+LDEAT+A+D E++ ++Q  +
Sbjct: 1449 RALLRKSKILVLDEATAAVDLETDNLIQTTI 1479


 Score = 49.2 bits (115), Expect = 5e-06
 Identities = 23/40 (57%), Positives = 31/40 (77%)

Query: 102 VGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 141
           +G++G  LSGGQKQRI++ARA  +N  I LLD+  SA+DA
Sbjct: 754 IGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDA 793


>sp|O15440|MRP5_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 (FRAGMENT).
           Length = 222
           
 Score = 69.1 bits (166), Expect = 5e-12
 Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 29/149 (19%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
           IDG  I  + +  LR  + ++ QEPVLF+ T+  N+       T+++I  A + ++  + 
Sbjct: 38  IDGVRISDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFN-QYTEDQIWDALERTHMKEC 96

Query: 63  IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
           I  LP                             K E+ V + G   S G++Q + IARA
Sbjct: 97  IAQLP----------------------------LKLESEVMENGDNFSVGERQLLCIARA 128

Query: 123 LVRNPKILLLDEATSALDAESETIVQAAL 151
           L+R+ KIL+LDEAT+A+D E++ ++Q  +
Sbjct: 129 LLRHCKILILDEATAAMDTETDLLIQETI 157


>sp|P36497|PEDD_PEDAC PEDIOCIN PA-1 TRANSPORT ATP-BINDING PROTEIN PEDD (PEDIOCIN ACH
           TRANSPORT ATP-BINDING PROTEIN PAPD).
           Length = 724
           
 Score = 68.7 bits (165), Expect = 7e-12
 Identities = 47/143 (32%), Positives = 71/143 (48%), Gaps = 29/143 (20%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYG-RLDVTQEEIERATKESNAYD 61
           I+ H+I  ++   LR+ I  V QEP +F+ ++ EN+  G R  VTQ+ I++A   +    
Sbjct: 547 INHHNISDISRTILRQYINYVPQEPFIFSGSVLENLLLGSRPGVTQQMIDQACSFAEIKT 606

Query: 62  FIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIAR 121
            I NLP                            Q + T + + G  LSGGQKQR++IAR
Sbjct: 607 DIENLP----------------------------QGYHTRLSESGFNLSGGQKQRLSIAR 638

Query: 122 ALVRNPKILLLDEATSALDAESE 144
           AL+   +  + DE+TS LD  +E
Sbjct: 639 ALLSPAQCFIFDESTSNLDTITE 661


>sp|P14772|YL15_YEAST PROBABLE ATP-DEPENDENT TRANSPORTER YLL015W.
            Length = 1559
            
 Score = 67.1 bits (161), Expect = 2e-11
 Identities = 44/152 (28%), Positives = 81/152 (52%), Gaps = 20/152 (13%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENI----RYGRLDVTQEEIERATKE 56
            + IDG DI  + +  LR  + ++ Q+   F  T+  N+    RY     +++E++RA ++
Sbjct: 1360 IIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRY-----SEDELKRAVEQ 1414

Query: 57   SNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQR 116
            ++          ++PHL    L   P   ++N          +  + + G+ LS GQ+Q 
Sbjct: 1415 AH----------LKPHLE-KMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQL 1463

Query: 117  IAIARALVRNPKILLLDEATSALDAESETIVQ 148
            + +ARAL+   KIL+LDEAT+++D E++ I+Q
Sbjct: 1464 LCLARALLNRSKILVLDEATASVDMETDKIIQ 1495


 Score = 53.9 bits (127), Expect = 2e-07
 Identities = 28/54 (51%), Positives = 39/54 (71%), Gaps = 1/54 (1%)

Query: 99  ETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAE-SETIVQAAL 151
           ETLVG++G  LSGGQK R+++ARA+     I LLD+  SA+DAE S+ I++  L
Sbjct: 760 ETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVL 813


>sp|P53706|HST6_CANAL ATP-DEPENDENT PERMEASE HST6 (STE6 HOMOLOG).
            Length = 1323
            
 Score = 66.3 bits (159), Expect = 4e-11
 Identities = 56/163 (34%), Positives = 78/163 (47%), Gaps = 23/163 (14%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYG-----------RLDVTQEE 49
            V I   ++  +N   L + I +V Q P  F+ TI +N+ YG              V+  E
Sbjct: 1107 VKIFNQNLYLINSGLLCQTIAIVPQFPKFFSGTIYDNLTYGINNTNSAGSNSSSSVSDSE 1166

Query: 50   IERATKESNAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFE---TLVGDRG 106
            I +  K  N + FI++LP          L++     N N     +E + E   T+     
Sbjct: 1167 IIKILKLVNLHQFIVSLPQ-------GLLTIMNDSDNDNDNGNENENENENGNTISTSSS 1219

Query: 107  TQL--SGGQKQRIAIARALVRNPKILLLDEATSALDAESETIV 147
            T    SGGQ Q +AIARAL+RNPKILLLDE TS LD  +  I+
Sbjct: 1220 TSFTFSGGQLQLLAIARALLRNPKILLLDECTSNLDPITTKII 1262


 Score = 55.0 bits (130), Expect = 9e-08
 Identities = 48/154 (31%), Positives = 74/154 (47%), Gaps = 33/154 (21%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFAT-TITENIRYGRLDVTQEEIERATKESNAYD 61
           ID   I  L+ +Y+ + I ++ Q PV+F   TI ENI    +D               YD
Sbjct: 434 IDTVSIDKLDPKYICQNITLLEQNPVIFDDKTIAENIAIAIVD--------------DYD 479

Query: 62  FIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIAR 121
            +  +P         Y  +  S   A +  +    K   L       LSGGQ+QRI+IAR
Sbjct: 480 SLQAIP---------YYLIEQSAHFALLSDLDLNMKVNHLT------LSGGQQQRISIAR 524

Query: 122 ALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           A ++N  +L++DE+ SALD E++   Q  ++KV+
Sbjct: 525 AYLKNSPVLIMDESFSALDTETK---QGLIEKVK 555


>sp|O15438|MRP3_HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 3 (FRAGMENT).
           Length = 485
           
 Score = 64.8 bits (155), Expect = 1e-10
 Identities = 45/159 (28%), Positives = 83/159 (51%), Gaps = 32/159 (20%)

Query: 3   IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENI-RYGRLDVTQEEIERATKESNAYD 61
           IDG ++  +    +R  + ++ ++P+LF+ T+  N+  +G    ++E+I  A + S+ + 
Sbjct: 307 IDGLNVADIGFHDVRCQMTIIPRDPILFSGTLRMNLDPFG--SYSEEDIWWALELSHLHT 364

Query: 62  FIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIAR 121
           F+ + P                   A +    SE          G  LS GQ+Q + +AR
Sbjct: 365 FVSSQP-------------------AGLDFQCSE---------GGENLSVGQRQLVCLAR 396

Query: 122 ALVRNPKILLLDEATSALDAESETIVQAALDKVQTQTCS 160
           AL+R  +IL+LDEAT+A+D E++ ++QA + + Q  TC+
Sbjct: 397 ALLRKSRILVLDEATAAIDLETDNLIQATI-RTQFDTCT 434


>sp|P53049|YOR1_YEAST OLIGOMYCIN RESISTANCE ATP-DEPENDENT PERMEASE YOR1.
            Length = 1477
            
 Score = 63.6 bits (152), Expect = 2e-10
 Identities = 46/151 (30%), Positives = 75/151 (49%), Gaps = 12/151 (7%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + ID  DI  L +  LR  + ++ Q+PVLF  TI +N     LD   E  +    ++   
Sbjct: 1271 ILIDNVDISQLGLFDLRRKLAIIPQDPVLFRGTIRKN-----LDPFNERTDDELWDALVR 1325

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
               +   D      LP + L     N   +  + +   +  V + G+  S G++Q +A+ 
Sbjct: 1326 GGAIAKDD------LPEVKLQKPDENGT-HGKMHKFHLDQAVEEEGSNFSLGERQLLALT 1378

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAAL 151
            RALVR  KIL+LDEATS++D E++  +Q  +
Sbjct: 1379 RALVRQSKILILDEATSSVDYETDGKIQTRI 1409


 Score = 43.4 bits (100), Expect = 3e-04
 Identities = 20/42 (47%), Positives = 29/42 (68%)

Query: 100 TLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 141
           T +G+RG  LSGGQK RI +AR++ +   I L D+  SA+D+
Sbjct: 701 TEIGERGITLSGGQKARINLARSVYKKKDIYLFDDVLSAVDS 742


>sp|Q10185|YAWB_SCHPO PROBABLE ATP-DEPENDENT PERMEASE C3F10.11C.
            Length = 1478
            
 Score = 63.2 bits (151), Expect = 3e-10
 Identities = 44/149 (29%), Positives = 71/149 (47%), Gaps = 29/149 (19%)

Query: 3    IDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAYDF 62
            +D  +I S+ +  LR  + ++ QE   F  TI EN+     + T EEI  A + ++   F
Sbjct: 1299 LDDINITSIGLHDLRSRLAIIPQENQAFEGTIRENLD-PNANATDEEIWHALEAASLKQF 1357

Query: 63   IMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARA 122
            I  L                   +  +Y  ++E          G  LS GQ+Q + + RA
Sbjct: 1358 IQTL-------------------DGGLYSRVTEG---------GANLSSGQRQLMCLTRA 1389

Query: 123  LVRNPKILLLDEATSALDAESETIVQAAL 151
            L+   ++LLLDEAT+A+D E++ IVQ  +
Sbjct: 1390 LLTPTRVLLLDEATAAVDVETDAIVQRTI 1418


 Score = 45.7 bits (106), Expect = 6e-05
 Identities = 22/42 (52%), Positives = 30/42 (71%)

Query: 99  ETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALD 140
           +T VG++G  LSGGQK RI++ARA+     I LLD+  SA+D
Sbjct: 711 QTEVGEKGISLSGGQKARISLARAVYSRSDIYLLDDILSAVD 752


>sp|P45171|POTA_HAEIN SPERMIDINE/PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTA.
           Length = 381
           
 Score = 61.7 bits (147), Expect = 9e-10
 Identities = 53/160 (33%), Positives = 71/160 (44%), Gaps = 40/160 (25%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFA-TTITENIRYG--RLDVTQEEIERATKES 57
           + +DG DI   N+   +  I  V Q   LF   TI EN+ +G     V  EEI+    E+
Sbjct: 76  IILDGEDIT--NVPAEKRHINTVFQSYALFPHMTIFENVAFGLRMQKVPNEEIKPRVLEA 133

Query: 58  NAYDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRI 117
                +  + D +P                                   TQLSGGQ+QRI
Sbjct: 134 LRMVQLEEMADRKP-----------------------------------TQLSGGQQQRI 158

Query: 118 AIARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
           AIARA+V  PK+LLLDE+ SALD +    +Q  L  +Q Q
Sbjct: 159 AIARAVVNKPKVLLLDESLSALDYKLRKQMQQELKMLQRQ 198


>sp|P33116|SPAT_BACSU SUBTILIN TRANSPORT ATP-BINDING PROTEIN SPAT.
           Length = 614
           
 Score = 60.5 bits (144), Expect = 2e-09
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 31/150 (20%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
           + I+G +I+ L++      I  + Q+ + +  T+ ENI +G++D    ++ +  K     
Sbjct: 411 ILINGINIKELDMDSYMNQIAALFQDFMKYEMTLKENIGFGQID----KLHQTNKMHEVL 466

Query: 61  DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVG---DRGTQLSGGQKQRI 117
           D +                       A+     S  +F+T +G   D G QLSGGQ Q+I
Sbjct: 467 DIV----------------------RADFLKSHSSYQFDTQLGLWFDEGRQLSGGQWQKI 504

Query: 118 AIARALVRNPKILLLDEATSALD--AESET 145
           A+ARA  R   + +LDE +SALD  AE ET
Sbjct: 505 ALARAYFREASLYILDEPSSALDPIAEKET 534


>sp|Q57213|YE74_HAEIN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN HI1474.
           Length = 199
           
 Score = 60.5 bits (144), Expect = 2e-09
 Identities = 38/106 (35%), Positives = 59/106 (54%), Gaps = 1/106 (0%)

Query: 82  PSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 141
           PS S+A   I++SE K + L+     QLSGG++QR+A+ARAL+  P +LLLDE  S+LD 
Sbjct: 93  PSASDAEQQILLSELKIDHLINRYPHQLSGGEQQRVALARALIYRPDLLLLDEPFSSLDW 152

Query: 142 ESETIVQAAL-DKVQTQTCSPSPCRTQPLDLKDISQYGQYVFSGVL 186
            S   +   L + +QT   +      +P + +  S     ++ G L
Sbjct: 153 SSRKDIWKVLKNLIQTNEITTILVTHEPKEAEYFSGKQIQLYQGQL 198


>sp|P54537|YQIZ_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BINDING PROTEIN IN
           BMRU-ANSR INTERGENIC REGION.
           Length = 240
           
 Score = 60.1 bits (143), Expect = 3e-09
 Identities = 51/147 (34%), Positives = 70/147 (46%), Gaps = 34/147 (23%)

Query: 12  NIRYLREMIGVVSQEPVLFA-TTITENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVR 70
           N   +RE IG+V Q   LF   T+ ENI Y  ++V +E  + A  +  A D +  +    
Sbjct: 71  NTLKVRENIGMVFQHFHLFPHKTVLENIMYAPVNVKKESKQAA--QEKAEDLLRKV---- 124

Query: 71  PHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKIL 130
                    L   R+                  D   +LSGGQKQR+AIARAL  NP I+
Sbjct: 125 --------GLFEKRN------------------DYPNRLSGGQKQRVAIARALAMNPDIM 158

Query: 131 LLDEATSALDAES-ETIVQAALDKVQT 156
           L DE TSALD E  + ++Q   + V+T
Sbjct: 159 LFDEPTSALDPEMVKEVLQVMKELVET 185


>sp|P74548|CYSA_SYNY3 SULFATE TRANSPORT ATP-BINDING PROTEIN CYSA.
           Length = 355
           
 Score = 59.7 bits (142), Expect = 4e-09
 Identities = 48/158 (30%), Positives = 75/158 (47%), Gaps = 36/158 (22%)

Query: 1   VFIDGHDIRSLNIRYLREMIGVVSQEPVLFA-TTITENIRYGRLDVTQEEIERATKESNA 59
           + I+G D   ++IR  +  IG V Q   LF   TI +NI +G                  
Sbjct: 59  IIINGQDATHVDIR--KRNIGFVFQHYALFKHLTIRQNIAFGL----------------- 99

Query: 60  YDFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAI 119
                   ++R H         P+++   +  ++S  + E L     +QLSGGQ+QR+A+
Sbjct: 100 --------EIRKH--------PPAKTKERVEELLSLIQLEGLGNRYPSQLSGGQRQRVAL 143

Query: 120 ARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
           ARAL   P++LLLDE   ALDA+    ++A L K+  +
Sbjct: 144 ARALAVQPQVLLLDEPFGALDAKVRKELRAWLRKLHDE 181


>sp|P30750|ABC_ECOLI ATP-BINDING PROTEIN ABC.
           Length = 343
           
 Score = 57.4 bits (136), Expect = 2e-08
 Identities = 30/47 (63%), Positives = 37/47 (77%), Gaps = 1/47 (2%)

Query: 107 TQLSGGQKQRIAIARALVRNPKILLLDEATSALD-AESETIVQAALD 152
           + LSGGQKQR+AIARAL  NPK+LL DEATSALD A + +I++   D
Sbjct: 139 SNLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKD 185


>sp|P23858|POTA_ECOLI SPERMIDINE/PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTA.
           Length = 378
           
 Score = 56.6 bits (134), Expect = 3e-08
 Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 18/133 (13%)

Query: 36  ENIRYGRLDVTQEEIERATKESNAYDFIMNLPDVRPHLWL-------------PYLSLAP 82
           E +  GR+ +  E+I     E+   + +     + PH+ +             P   + P
Sbjct: 67  ETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITP 126

Query: 83  SRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAE 142
               A   + +     ET    +  QLSGGQ+QR+AIARA+V  P++LLLDE+ SALD +
Sbjct: 127 RVMEALRMVQL-----ETFAQRKPHQLSGGQQQRVAIARAVVNKPRLLLLDESLSALDYK 181

Query: 143 SETIVQAALDKVQ 155
               +Q  L  +Q
Sbjct: 182 LRKQMQNELKALQ 194


>sp|P77795|YDCT_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YDCT.
           Length = 337
           
 Score = 56.6 bits (134), Expect = 3e-08
 Identities = 28/49 (57%), Positives = 36/49 (73%)

Query: 107 TQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKVQ 155
           +QLSGGQ+QR+AIARALV  P++LLLDE   ALD +    +Q  L K+Q
Sbjct: 133 SQLSGGQRQRVAIARALVNEPRVLLLDEPLGALDLKLREQMQLELKKLQ 181


>sp|P39109|YCFI_YEAST METAL RESISTANCE PROTEIN YCF1 (YEAST CADMIUM FACTOR 1).
            Length = 1515
            
 Score = 55.8 bits (132), Expect = 5e-08
 Identities = 40/151 (26%), Positives = 71/151 (46%), Gaps = 28/151 (18%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + ID   I  + +  LR  + ++ Q+  +F  T+ ENI       T E I RA + S+  
Sbjct: 1330 IVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPIN-QYTDEAIWRALELSHLK 1388

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
            + ++++                           S    +  + + G  LS GQ+Q + +A
Sbjct: 1389 EHVLSM---------------------------SNDGLDAQLTEGGGNLSVGQRQLLCLA 1421

Query: 121  RALVRNPKILLLDEATSALDAESETIVQAAL 151
            RA++   KIL+LDEAT+A+D E++ +VQ  +
Sbjct: 1422 RAMLVPSKILVLDEATAAVDVETDKVVQETI 1452


 Score = 44.1 bits (102), Expect = 2e-04
 Identities = 20/42 (47%), Positives = 30/42 (70%)

Query: 99  ETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALD 140
           +TLVG++G  LSGGQK R+++ARA+       LLD+  +A+D
Sbjct: 743 KTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVD 784


>sp|P75059|POTA_MYCPN SPERMIDINE/PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTA HOMOLOG.
           Length = 560
           
 Score = 55.4 bits (131), Expect = 7e-08
 Identities = 32/64 (50%), Positives = 41/64 (64%), Gaps = 6/64 (9%)

Query: 101 LVGDRGTQ------LSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKV 154
           LVG +G +      LSGG KQR+A+AR+LV  P ILLLDE  SALDA+    +Q  L K+
Sbjct: 335 LVGLKGNEDKLPEELSGGMKQRVALARSLVIEPDILLLDEPLSALDAKVRKNLQKELQKI 394

Query: 155 QTQT 158
             Q+
Sbjct: 395 HQQS 398


>sp|P44785|ABC_HAEIN ATP-BINDING PROTEIN ABC.
           Length = 345
           
 Score = 55.0 bits (130), Expect = 9e-08
 Identities = 28/43 (65%), Positives = 37/43 (85%), Gaps = 1/43 (2%)

Query: 107 TQLSGGQKQRIAIARALVRNPKILLLDEATSALD-AESETIVQ 148
           + LSGGQKQR+AIARAL  +PK+LL DEATSALD A +++I++
Sbjct: 139 SNLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILK 181


>sp|Q58206|Y796_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796.
           Length = 235
           
 Score = 55.0 bits (130), Expect = 9e-08
 Identities = 27/59 (45%), Positives = 37/59 (61%)

Query: 99  ETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
           E     +  QLSGGQ+QR+AIARAL  NP I+L DE T ALD+++   +   L K+  +
Sbjct: 136 ERFANHKPNQLSGGQQQRVAIARALANNPPIILADEPTGALDSKTGEKIMQLLKKLNEE 194


>sp|P27675|GLNQ_BACST GLUTAMINE TRANSPORT ATP-BINDING PROTEIN GLNQ.
           Length = 242
           
 Score = 54.7 bits (129), Expect = 1e-07
 Identities = 45/136 (33%), Positives = 62/136 (45%), Gaps = 33/136 (24%)

Query: 9   RSLNIRYLREMIGVVSQEPVLFA-TTITENIRYGRLDVTQEEIERATKESNAYDFIMNLP 67
           + ++I  LR  IG+V Q   L+   T+ +NI    + V +   E+  KE+  Y       
Sbjct: 68  KHIDINQLRRNIGMVFQHFNLYPHMTVLQNITLAPMKVLRIP-EKEAKETAMY------- 119

Query: 68  DVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNP 127
                    YL        AN Y                ++LSGGQ+QR+AIAR L   P
Sbjct: 120 ---------YLEKVGIPDKANAY---------------PSELSGGQQQRVAIARGLAMKP 155

Query: 128 KILLLDEATSALDAES 143
           KI+L DE TSALD E+
Sbjct: 156 KIMLFDEPTSALDPET 171


>sp|P75957|YCFV_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YCFV.
           Length = 228
           
 Score = 54.7 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 49/88 (55%), Gaps = 4/88 (4%)

Query: 60  YDFIMNLPDVRP--HLWLPYL--SLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQ 115
           Y F   LPD     ++ +P L     P+  N+    M+     +     R ++LSGG++Q
Sbjct: 88  YQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLKAVGLDHRANHRPSELSGGERQ 147

Query: 116 RIAIARALVRNPKILLLDEATSALDAES 143
           R+AIARALV NP+++L DE T  LDA +
Sbjct: 148 RVAIARALVNNPRLVLADEPTGNLDARN 175


>sp|P15031|FECE_ECOLI IRON(III) DICITRATE TRANSPORT ATP-BINDING PROTEIN FECE.
           Length = 255
           
 Score = 54.3 bits (128), Expect = 2e-07
 Identities = 31/107 (28%), Positives = 55/107 (50%), Gaps = 6/107 (5%)

Query: 74  WLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLD 133
           WL       +  NA + + +++ +   L   R T+LSGGQ+QR  +A  L +N  ++LLD
Sbjct: 104 WLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVVLLD 163

Query: 134 EATSALDAESETIVQAALDKVQTQTCSPSPCRTQPLDLKDISQYGQY 180
           E T+ LD   +  +   + +++TQ       +T    L D++Q  +Y
Sbjct: 164 EPTTYLDINHQVDLMRLMGELRTQG------KTVVAVLHDLNQASRY 204


>sp|Q47538|TAUB_ECOLI TAURINE TRANSPORT ATP-BINDING PROTEIN TAUB.
           Length = 255
           
 Score = 54.3 bits (128), Expect = 2e-07
 Identities = 28/51 (54%), Positives = 36/51 (69%)

Query: 108 QLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQT 158
           QLSGGQ+QR+ IARAL  NP++LLLDE   ALDA +   +Q  L K+  +T
Sbjct: 128 QLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTRDQMQTLLLKLWQET 178


>sp|Q57855|Y412_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0412.
           Length = 267
           
 Score = 54.3 bits (128), Expect = 2e-07
 Identities = 30/65 (46%), Positives = 43/65 (66%), Gaps = 6/65 (9%)

Query: 96  QKFETLVGDRGT------QLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQA 149
           +KF  +VG  G       QLSGG +QR+AIAR L  +P+I+L+DE  +ALDA++  I+Q 
Sbjct: 129 KKFIKMVGLEGFEDAYPYQLSGGMQQRVAIARTLANDPEIVLMDEPFAALDAQTRNILQN 188

Query: 150 ALDKV 154
            L K+
Sbjct: 189 ELLKI 193


>sp|P47705|Y467_MYCGE HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG467.
           Length = 311
           
 Score = 54.3 bits (128), Expect = 2e-07
 Identities = 28/54 (51%), Positives = 39/54 (71%), Gaps = 3/54 (5%)

Query: 108 QLSGGQKQRIAIARALVRNPKILLLDEATSALDAES-ETIVQ--AALDKVQTQT 158
           ++SGGQKQR+AIARA+++ PK+LL DE T ALD+ S E I+     ++K   QT
Sbjct: 223 EMSGGQKQRVAIARAIIKEPKLLLCDEPTGALDSNSAENIINLLQTINKTYKQT 276


>sp|P75110|Y467_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG467 HOMOLOG.
           Length = 339
           
 Score = 54.3 bits (128), Expect = 2e-07
 Identities = 24/50 (48%), Positives = 36/50 (72%)

Query: 108 QLSGGQKQRIAIARALVRNPKILLLDEATSALDAESETIVQAALDKVQTQ 157
           ++SGGQKQR+AIARA+++ P++LL DE T ALD+ S   + A L  +  +
Sbjct: 251 EMSGGQKQRVAIARAIIKEPRLLLCDEPTGALDSNSAENIIALLQAINKE 300


>sp|P21441|MDR_LEITA MULTIDRUG RESISTANCE PROTEIN (P-GLYCOPROTEIN).
           Length = 1548
           
 Score = 53.9 bits (127), Expect = 2e-07
 Identities = 35/91 (38%), Positives = 54/91 (58%), Gaps = 5/91 (5%)

Query: 99  ETLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAE-SETIVQ-AALDKVQT 156
           +T +G+ G  LSGGQK R+++ARA+  N  + LLD+  SALDA   + IVQ   L +++ 
Sbjct: 747 DTEIGEMGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGQRIVQDVILGRLRG 806

Query: 157 QTCSPSPCRTQPLDLKD---ISQYGQYVFSG 184
           +T   +  +   L L D   + Q+G  VF+G
Sbjct: 807 KTRVLATHQIHLLPLADYIVVLQHGSIVFAG 837


 Score = 42.2 bits (97), Expect = 7e-04
 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 30/152 (19%)

Query: 1    VFIDGHDIRSLNIRYLREMIGVVSQEPVLFATTITENIRYGRLDVTQEEIERATKESNAY 60
            + ++G ++ +  +R +R    ++ Q+PVLF  T+ +N+    L+ +  E+  A       
Sbjct: 1344 IHVNGREMSAYGLRDVRRHFSMIPQDPVLFDGTVRQNVD-PFLEASSAEVWAA------- 1395

Query: 61   DFIMNLPDVRPHLWLPYLSLAPSRSNANIYIMISEQKFETLVGDRGTQLSGGQKQRIAIA 120
                             L L   R      +    +  ++ V + G+  S GQ+Q + +A
Sbjct: 1396 -----------------LELVGLRER----VASESEGIDSRVLEGGSNYSVGQRQLMCMA 1434

Query: 121  RALV-RNPKILLLDEATSALDAESETIVQAAL 151
            RAL+ R    +L+DEAT+ +D   +  +QA +
Sbjct: 1435 RALLKRGSGFILMDEATANIDPALDRQIQATV 1466


>sp|Q52666|BZTD_RHOCA GLUTAMATE/GLUTAMINE/ASPARTATE/ASPARAGINE TRANSPORT ATP-BINDING
           PROTEIN BZTD.
           Length = 263
           
 Score = 53.5 bits (126), Expect = 3e-07
 Identities = 30/57 (52%), Positives = 39/57 (67%), Gaps = 6/57 (10%)

Query: 108 QLSGGQKQRIAIARALVRNPKILLLDEATSALDAES-----ETIVQAALDKVQTQTC 159
           QLSGGQ+QR+AIAR+L   PKI+L DE TSALD E      +T++Q A ++  T  C
Sbjct: 157 QLSGGQQQRVAIARSLCMKPKIMLFDEPTSALDPEMIKEVLDTMIQLA-EEGMTMLC 212


  Database: swissprot36
    Posted date:  Feb 26, 1999  3:43 PM
  Number of letters in database: 26,840,295
  Number of sequences in database:  74,019
  
Lambda     K      H
   0.317    0.133    0.372 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9379942
Number of Sequences: 74019
Number of extensions: 346253
Number of successful extensions: 1621
Number of sequences better than 10.0: 412
Number of HSP's better than 10.0 without gapping: 393
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 974
Number of HSP's gapped (non-prelim): 592
length of query: 201
length of database: 26840295
effective HSP length: 53
effective length of query: 148
effective length of database: 22917288
effective search space: 3391758624
effective search space used: 3391758624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 62 (28.6 bits)

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Last modified: Thu, 27 May 1999, [email protected]